Detailed information of TA system TA057982

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-SprA2AS/-
• Location: 2405495..2405679
• Replicon: chromosome
• Accession: NZ_CP013132
• Organism: Staphylococcus aureus strain FORC_026

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: A0A2P7CQJ7
• Locus tag: FORC26_RS12535
• Protein ID: WP_000482647.1
• Coordinates: 2405572..2405679 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	2405495..2405555 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FORC26_RS12505	2400969..2401136	-	168	WP_001790576.1	hypothetical protein	-
FORC26_RS12515	2401367..2403100	-	1734	WP_000486494.1	ABC transporter ATP-binding protein/permease	-
FORC26_RS12520	2403125..2404888	-	1764	WP_001064816.1	ABC transporter ATP-binding protein/permease	-
-	2405495..2405555	+	61	-	-	Antitoxin
FORC26_RS12535	2405572..2405679	-	108	WP_000482647.1	type I toxin-antitoxin system Fst family toxin	Toxin
FORC26_RS12540	2405813..2406199	-	387	WP_000779360.1	flippase GtxA	-
FORC26_RS12545	2406457..2407599	+	1143	WP_001176871.1	glycerate kinase	-
FORC26_RS12550	2407659..2408318	+	660	WP_000831301.1	membrane protein	-
FORC26_RS12555	2408500..2409711	+	1212	WP_001192075.1	multidrug effflux MFS transporter	-
FORC26_RS12560	2409834..2410307	-	474	WP_000456497.1	GyrI-like domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 4012.76 Da
• Isoelectric Point: 10.4935

>T57982 WP_000482647.1 NZ_CP013132:c2405679-2405572 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Nucleotide

• Length: 108 bp

>T57982 NZ_CP013132:c2405679-2405572 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin

Nucleotide

• Length: 61 bp

>AT57982 NZ_CP013132:2405495-2405555 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Structures

Toxin

• AlphaFold DB: A0A2P7CQJ7

Antitoxin