57980

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-sprA1AS/-
Location 2127054..2127251 Replicon chromosome
Accession NZ_CP013132
Organism Staphylococcus aureus strain FORC_026

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag FORC26_RS11005 Protein ID WP_001802298.1
Coordinates 2127147..2127251 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2127054..2127092 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FORC26_RS10985 2123238..2123903 - 666 WP_001024095.1 SDR family oxidoreductase -
FORC26_RS10990 2124055..2124375 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
FORC26_RS10995 2124377..2125357 + 981 WP_000019743.1 CDF family zinc efflux transporter CzrB -
FORC26_RS11000 2125623..2126714 + 1092 WP_000495683.1 hypothetical protein -
- 2127054..2127092 + 39 - - Antitoxin
FORC26_RS11005 2127147..2127251 - 105 WP_001802298.1 hypothetical protein Toxin
FORC26_RS11020 2127931..2128089 + 159 WP_001792784.1 hypothetical protein -
FORC26_RS11030 2128748..2129605 - 858 WP_000370917.1 Cof-type HAD-IIB family hydrolase -
FORC26_RS11035 2129673..2130455 - 783 WP_000908178.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T57980 WP_001802298.1 NZ_CP013132:c2127251-2127147 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T57980 NZ_CP013132:c2127251-2127147 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 39 bp

>AT57980 NZ_CP013132:2127054-2127092 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References