57974

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1837544..1837732 Replicon chromosome
Accession NZ_CP013132
Organism Staphylococcus aureus strain FORC_026

Toxin (Protein)


Gene name sprA1 Uniprot ID Q8VVS0
Locus tag FORC26_RS14400 Protein ID WP_001791613.1
Coordinates 1837544..1837636 (+) Length 31 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1837673..1837732 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FORC26_RS09235 1833213..1833839 + 627 WP_000669017.1 hypothetical protein -
FORC26_RS09240 1833880..1834221 + 342 WP_000627541.1 DUF3969 family protein -
FORC26_RS09245 1834322..1834894 + 573 WP_000414202.1 hypothetical protein -
FORC26_RS09250 1835092..1835649 - 558 Protein_1705 ImmA/IrrE family metallo-endopeptidase -
FORC26_RS09260 1836023..1836199 - 177 WP_000375477.1 hypothetical protein -
FORC26_RS09265 1836210..1836593 - 384 WP_000070814.1 hypothetical protein -
FORC26_RS09275 1837197..1837340 - 144 WP_001549059.1 transposase -
FORC26_RS14400 1837544..1837636 + 93 WP_001791613.1 type I toxin-antitoxin system Fst family toxin Toxin
- 1837673..1837732 - 60 - - Antitoxin
FORC26_RS09280 1837768..1837869 + 102 WP_001791893.1 hypothetical protein -
FORC26_RS09285 1837847..1838023 - 177 Protein_1711 transposase -
FORC26_RS09290 1838217..1838594 - 378 Protein_1712 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - lukD / hlgA 1831449..1890562 59113


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 31 a.a.        Molecular weight: 3471.23 Da        Isoelectric Point: 9.7333

>T57974 WP_001791613.1 NZ_CP013132:1837544-1837636 [Staphylococcus aureus]
MLIIFVHIIAPVISGCAVAYYTYWLSKRNK

Download         Length: 93 bp

>T57974 NZ_CP013132:1837544-1837636 [Staphylococcus aureus]
TTGCTAATCATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCTGTTGCGTATTATACTTATTGGCTTAGTAA
ACGCAACAAATAA

Antitoxin


Download         Length: 60 bp

>AT57974 NZ_CP013132:c1837732-1837673 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGTGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB Q8VVS0

Antitoxin

Download structure file

References