Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) sprG-sprF/-
Location 1786221..1786480 Replicon chromosome
Accession NZ_CP013114
Organism Staphylococcus equorum strain KS1039

Toxin (Protein)


Gene name SprG2 Uniprot ID -
Locus tag SE1039_RS13600 Protein ID WP_002511402.1
Coordinates 1786373..1786480 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 1786221..1786383 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SE1039_RS08680 1781710..1782747 - 1038 WP_056935773.1 lactonase family protein -
SE1039_RS08685 1782924..1783334 + 411 WP_002507169.1 YolD-like family protein -
SE1039_RS13780 1783902..1784072 - 171 WP_002507168.1 hypothetical protein -
SE1039_RS08690 1784567..1785607 + 1041 WP_056935774.1 choloylglycine hydrolase -
SE1039_RS13785 1785915..1786085 + 171 WP_002507166.1 tyrosine-type recombinase/integrase -
- 1786221..1786383 + 163 - - Antitoxin
SE1039_RS13600 1786373..1786480 - 108 WP_002511402.1 putative holin-like toxin Toxin
SE1039_RS08695 1786846..1787697 - 852 WP_021339982.1 DUF4097 family beta strand repeat protein -
SE1039_RS08700 1787694..1788254 - 561 WP_002511403.1 DUF1700 domain-containing protein -
SE1039_RS13900 1788626..1788787 - 162 WP_196368299.1 hypothetical protein -
SE1039_RS08710 1789003..1789563 + 561 WP_002507158.1 thioredoxin family protein -
SE1039_RS08715 1789646..1790374 - 729 WP_002507157.1 ABC transporter permease subunit -
SE1039_RS08720 1790374..1791246 - 873 WP_002507156.1 ABC transporter ATP-binding protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(4-35)


Sequences


Toxin        


Download         Length: 36 a.a.        Molecular weight: 3756.72 Da        Isoelectric Point: 10.4997

>T57947 WP_002511402.1 NZ_CP013114:c1786480-1786373 [Staphylococcus equorum]
VVPIVEALHLMLGFGTFIVTLLGLVVAIVKLSHKK

Download         Length: 108 bp

>T57947 NZ_CP013114:c1786480-1786373 [Staphylococcus equorum]
GTGGTTCCAATTGTAGAAGCACTACACTTAATGTTAGGTTTCGGTACTTTCATCGTTACCTTATTAGGTTTAGTGGTTGC
AATTGTTAAATTAAGCCATAAAAAATAA

Antitoxin


Download         Length: 163 bp

>AT57947 NZ_CP013114:1786221-1786383 [Staphylococcus equorum]
ATTTGATAATATTTTTATGTTGTGGTAATTTATATATAGAAAAAGGGCAACACACCATAAGTGCATCGCCCTAATGAGCC
CGTTAAAAAGACGGTGGCTGGAATTTAATAATGATTAAATAATCATCTCATCCTCGCCAAAGTTAGAGATGGTTATTTTT
TAT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References