Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/MqsA(antitoxin)
Location 2013074..2013742 Replicon chromosome
Accession NZ_CP013103
Organism Paraburkholderia caribensis strain MWAP64

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag AN416_RS25075 Protein ID WP_060605493.1
Coordinates 2013074..2013415 (+) Length 114 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag AN416_RS25080 Protein ID WP_060605496.1
Coordinates 2013431..2013742 (+) Length 104 a.a.

Genomic Context

AN416_RS25055AN416_RS25060AN416_RS25065AN416_RS25070AN416_RS25075AN416_RS25080AN416_RS41370AN416_RS25085AN416_RS25090
Location: 2008694..2009671 (978 bp)
Type: Others
Protein ID: WP_054933738.1
Location: 2009710..2010714 (1005 bp)
Type: Others
Protein ID: WP_060605483.1
Location: 2010730..2011842 (1113 bp)
Type: Others
Protein ID: WP_060605486.1
Location: 2011845..2012819 (975 bp)
Type: Others
Protein ID: WP_060605490.1
Location: 2013074..2013415 (342 bp)
Type: Toxin
Protein ID: WP_060605493.1
Location: 2013431..2013742 (312 bp)
Type: Antitoxin
Protein ID: WP_060605496.1
Location: 2015331..2015540 (210 bp)
Type: Others
Protein ID: WP_148654612.1
Location: 2013837..2015303 (1467 bp)
Type: Others
Protein ID: WP_054933743.1
Location: 2016212..2017495 (1284 bp)
Type: Others
Protein ID: WP_054933746.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
AN416_RS250552008694..2009671+978WP_054933738.1thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha-
AN416_RS250602009710..2010714+1005WP_060605483.1alpha-ketoacid dehydrogenase subunit beta-
AN416_RS250652010730..2011842+1113WP_060605486.1acetoin dehydrogenase dihydrolipoyllysine-residue acetyltransferase subunit-
AN416_RS250702011845..2012819+975WP_060605490.1lipoyl synthase-
AN416_RS250752013074..2013415+342WP_060605493.1hypothetical proteinToxin
AN416_RS250802013431..2013742+312WP_060605496.1helix-turn-helix domain-containing proteinAntitoxin
AN416_RS250852013837..2015303-1467WP_054933743.1NAD-dependent succinate-semialdehyde dehydrogenase-
AN416_RS413702015331..2015540+210WP_148654612.1hypothetical protein-
AN416_RS250902016212..2017495-1284WP_054933746.14-aminobutyrate--2-oxoglutarate transaminase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-87)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 13194.11 Da        Isoelectric Point: 9.6373

>T57913 WP_060605493.1 NZ_CP013103:2013074-2013415 [Paraburkholderia caribensis]
VAATFVELGPFRRWRDDYLTDDEYRALQIVLMQNPEAGDVIRGTGGLRKLRFGDARRGKGKRGGLRVIYYYWVKGPEFWM
FTLYDKDEAEDLSSKERGVLSEMLREVIKLANR

Download         Length: 342 bp

>T57913 NZ_CP013103:2013074-2013415 [Paraburkholderia caribensis]
GTGGCGGCGACTTTCGTCGAGCTAGGCCCATTTCGCCGGTGGCGGGACGACTATCTGACGGACGACGAATATCGCGCGCT
TCAGATTGTGCTGATGCAGAACCCGGAAGCAGGGGATGTCATCAGGGGAACGGGTGGGCTGCGCAAACTCCGTTTCGGCG
ACGCACGGCGCGGGAAGGGAAAGCGCGGCGGGCTCAGGGTGATCTACTACTACTGGGTAAAGGGCCCCGAGTTCTGGATG
TTCACGCTGTACGACAAGGACGAAGCTGAAGACCTGTCGTCGAAGGAACGAGGGGTTCTCTCCGAGATGCTGAGAGAAGT
CATCAAGCTTGCGAATCGATAA

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11827.65 Da        Isoelectric Point: 9.7238

>AT57913 WP_060605496.1 NZ_CP013103:2013431-2013742 [Paraburkholderia caribensis]
MKRNLLAELTEGLEELKSAHEGKTTLHKVKVEIRDKLEVTAEEIRAVRESINASQAVMARRLRVNERTYQNWEQGRAKPN
AQAAVLIKLVEKHPETIQMLETL

Download         Length: 312 bp

>AT57913 NZ_CP013103:2013431-2013742 [Paraburkholderia caribensis]
ATGAAACGGAATCTGTTAGCCGAATTGACGGAAGGGCTCGAAGAACTCAAGTCCGCTCACGAAGGCAAGACCACACTTCA
CAAGGTCAAGGTTGAGATTCGTGACAAGCTGGAAGTAACGGCCGAGGAGATCCGTGCCGTCCGCGAATCCATCAACGCGT
CACAGGCGGTCATGGCACGCCGTCTGCGCGTGAACGAGCGGACGTACCAGAATTGGGAGCAAGGGAGGGCGAAACCGAAC
GCTCAGGCTGCCGTGCTGATCAAGCTGGTTGAAAAGCATCCTGAGACGATCCAGATGCTCGAAACCTTATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References