Detailed information of TA system TA057559

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1802681..1802861
• Replicon: chromosome
• Accession: NZ_CP012976
• Organism: Staphylococcus aureus strain ST20130942

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: SAST42_RS14675
• Protein ID: WP_001801861.1
• Coordinates: 1802681..1802776 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1802804..1802861 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SAST42_RS08730	1797843..1798493	+	651	WP_072470537.1	excalibur calcium-binding domain-containing protein	-
SAST42_RS08735	1798574..1799569	+	996	WP_000070641.1	DUF4352 domain-containing protein	-
SAST42_RS08740	1799644..1800270	+	627	WP_000669026.1	hypothetical protein	-
SAST42_RS08745	1800311..1800652	+	342	WP_000627537.1	DUF3969 family protein	-
SAST42_RS08750	1800753..1801325	+	573	WP_000414215.1	hypothetical protein	-
SAST42_RS14325	1801524..1802536	-	1013	Protein_1678	IS3 family transposase	-
SAST42_RS14675	1802681..1802776	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1802804..1802861	-	58	-	-	Antitoxin
SAST42_RS08770	1802899..1803000	+	102	WP_001792025.1	hypothetical protein	-
SAST42_RS14680	1802978..1803139	-	162	Protein_1681	transposase	-
SAST42_RS08775	1803130..1803624	-	495	Protein_1682	transposase	-
SAST42_RS08780	1804076..1805305	-	1230	WP_047230715.1	restriction endonuclease subunit S	-
SAST42_RS08785	1805298..1806853	-	1556	Protein_1684	type I restriction-modification system subunit M	-
SAST42_RS08790	1807018..1807152	-	135	Protein_1685	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T57559 WP_001801861.1 NZ_CP012976:1802681-1802776 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T57559 NZ_CP012976:1802681-1802776 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT57559 NZ_CP012976:c1802861-1802804 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin