Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2416141..2416324 Replicon chromosome
Accession NZ_CP012970
Organism Staphylococcus aureus strain ST20130939

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag SAST39_RS12215 Protein ID WP_000482647.1
Coordinates 2416217..2416324 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2416141..2416200 (+)

Genomic Context


--SAST39_RS12225SAST39_RS12230SAST39_RS12235SAST39_RS12190SAST39_RS12200SAST39_RS12205SAST39_RS12215SAST39_RS12220SAST39_RS12240
Location: 2416141..2416200 (60 bp)
Type: Antitoxin
Protein ID: -
Location: 2417102..2418244 (1143 bp)
Type: Others
Protein ID: WP_001176863.1
Location: 2418304..2418963 (660 bp)
Type: Others
Protein ID: WP_000831295.1
Location: 2419145..2420356 (1212 bp)
Type: Others
Protein ID: WP_001192075.1
Location: 2411595..2411762 (168 bp)
Type: Others
Protein ID: WP_001792506.1
Location: 2411993..2413726 (1734 bp)
Type: Others
Protein ID: WP_000486496.1
Location: 2413751..2415514 (1764 bp)
Type: Others
Protein ID: WP_001064836.1
Location: 2416217..2416324 (108 bp)
Type: Toxin
Protein ID: WP_000482647.1
Location: 2416458..2416844 (387 bp)
Type: Others
Protein ID: WP_000779360.1
Location: 2420479..2420952 (474 bp)
Type: Others
Protein ID: WP_000456492.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
SAST39_RS121902411595..2411762-168WP_001792506.1hypothetical protein-
SAST39_RS122002411993..2413726-1734WP_000486496.1ABC transporter ATP-binding protein/permease-
SAST39_RS122052413751..2415514-1764WP_001064836.1ABC transporter ATP-binding protein/permease-
-2416141..2416200+60--Antitoxin
SAST39_RS122152416217..2416324-108WP_000482647.1type I toxin-antitoxin system Fst family toxinToxin
SAST39_RS122202416458..2416844-387WP_000779360.1flippase GtxA-
SAST39_RS122252417102..2418244+1143WP_001176863.1glycerate kinase-
SAST39_RS122302418304..2418963+660WP_000831295.1hypothetical protein-
SAST39_RS122352419145..2420356+1212WP_001192075.1multidrug effflux MFS transporter-
SAST39_RS122402420479..2420952-474WP_000456492.1GyrI-like domain-containing protein-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T57529 WP_000482647.1 NZ_CP012970:c2416324-2416217 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T57529 NZ_CP012970:c2416324-2416217 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 60 bp

>AT57529 NZ_CP012970:2416141-2416200 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGG

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
AlphaFold DBA0A2P7CQJ7


Antitoxin

Download structure file

References