Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2416141..2416324 Replicon chromosome
Accession NZ_CP012970
Organism Staphylococcus aureus strain ST20130939

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag SAST39_RS12215 Protein ID WP_000482647.1
Coordinates 2416217..2416324 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2416141..2416200 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAST39_RS12190 2411595..2411762 - 168 WP_001792506.1 hypothetical protein -
SAST39_RS12200 2411993..2413726 - 1734 WP_000486496.1 ABC transporter ATP-binding protein/permease -
SAST39_RS12205 2413751..2415514 - 1764 WP_001064836.1 ABC transporter ATP-binding protein/permease -
- 2416141..2416200 + 60 - - Antitoxin
SAST39_RS12215 2416217..2416324 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
SAST39_RS12220 2416458..2416844 - 387 WP_000779360.1 flippase GtxA -
SAST39_RS12225 2417102..2418244 + 1143 WP_001176863.1 glycerate kinase -
SAST39_RS12230 2418304..2418963 + 660 WP_000831295.1 hypothetical protein -
SAST39_RS12235 2419145..2420356 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
SAST39_RS12240 2420479..2420952 - 474 WP_000456492.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T57529 WP_000482647.1 NZ_CP012970:c2416324-2416217 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T57529 NZ_CP012970:c2416324-2416217 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 60 bp

>AT57529 NZ_CP012970:2416141-2416200 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References