Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-sprA1AS/-
Location 2136502..2136699 Replicon chromosome
Accession NZ_CP012970
Organism Staphylococcus aureus strain ST20130939

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag SAST39_RS10720 Protein ID WP_001802298.1
Coordinates 2136595..2136699 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2136502..2136540 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAST39_RS10705 2131775..2132755 + 981 WP_000019739.1 CDF family zinc efflux transporter CzrB -
SAST39_RS10710 2133021..2134112 + 1092 WP_000495672.1 hypothetical protein -
SAST39_RS10715 2134141..2135787 - 1647 WP_000277718.1 IS1182 family transposase -
- 2136502..2136540 + 39 - - Antitoxin
SAST39_RS10720 2136595..2136699 - 105 WP_001802298.1 hypothetical protein Toxin
SAST39_RS14305 2137379..2137537 + 159 WP_001792784.1 hypothetical protein -
SAST39_RS10725 2138196..2139053 - 858 WP_000370931.1 Cof-type HAD-IIB family hydrolase -
SAST39_RS10730 2139121..2139903 - 783 WP_000908174.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 2134141..2135787 1646


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T57527 WP_001802298.1 NZ_CP012970:c2136699-2136595 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T57527 NZ_CP012970:c2136699-2136595 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 39 bp

>AT57527 NZ_CP012970:2136502-2136540 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References