Detailed information of TA system TA057513

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): holin-SprF1/-
• Location: 869362..869732
• Replicon: chromosome
• Accession: NZ_CP012968
• Organism: Staphylococcus sp. AntiMn-1 isolate deep-sea sediment of east Pacific Nodule Province

Toxin (Protein)

• Gene name: holin
• Uniprot ID: -
• Locus tag: AOB58_RS04310
• Protein ID: WP_064783025.1
• Coordinates: 869362..869583 (-)
• Length: 74 a.a.

Antitoxin (RNA)

Gene name	SprF1
Locus tag	-
Coordinates	869634..869732 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AOB58_RS04295	864735..865292	+	558	WP_046465190.1	GNAT family N-acetyltransferase	-
AOB58_RS04300	865354..867237	-	1884	WP_046465189.1	glycosyltransferase family 2 protein	-
AOB58_RS13550	867544..867651	-	108	WP_158649099.1	hypothetical protein	-
AOB58_RS04305	867687..868037	-	351	WP_064783024.1	hypothetical protein	-
AOB58_RS13285	868034..868249	-	216	WP_082920397.1	hypothetical protein	-
AOB58_RS13290	868685..868792	-	108	WP_021338681.1	putative holin-like toxin	-
AOB58_RS13295	869091..869207	-	117	WP_165349553.1	putative holin-like toxin	-
AOB58_RS04310	869362..869583	-	222	WP_064783025.1	phage holin	Toxin
-	869634..869732	+	99	NuclAT_1	-	Antitoxin
AOB58_RS04320	870420..870929	-	510	WP_002507954.1	metallophosphoesterase	-
AOB58_RS04325	870929..871510	-	582	WP_002507955.1	XTP/dITP diphosphatase	-
AOB58_RS04330	871528..872322	-	795	WP_002507956.1	glutamate racemase	-
AOB58_RS04335	872598..873419	-	822	WP_002507957.1	succinate dehydrogenase iron-sulfur subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Holin (7-57)

Sequences

Toxin

Protein

• Length: 74 a.a.
• Molecular weight: 8134.67 Da
• Isoelectric Point: 6.1486

>T57513 WP_064783025.1 NZ_CP012968:c869583-869362 [Staphylococcus sp. AntiMn-1]
MDVKVTVIVRVLSLILVLVNQWLSNKGVSPIPVDESTLMTIAVALITMLKDNPFTDAAKGSFFKSYTYQLEIF

Nucleotide

• Length: 222 bp

>T57513 NZ_CP012968:c869583-869362 [Staphylococcus sp. AntiMn-1]
ATGGATGTAAAAGTAACAGTAATCGTAAGAGTATTAAGTTTAATTTTGGTGTTAGTGAACCAGTGGTTGTCAAATAAAGG
AGTGAGTCCTATTCCAGTGGATGAGTCAACACTAATGACTATCGCAGTCGCATTAATCACGATGTTGAAAGATAACCCAT
TTACAGATGCAGCTAAGGGTTCTTTTTTTAAATCTTATACTTATCAGCTTGAAATATTTTGA

Antitoxin

Nucleotide

• Length: 99 bp

>AT57513 NZ_CP012968:869634-869732 [Staphylococcus sp. AntiMn-1]
ATTTGATAATATTTATATGTTGTGTTAATTTATATATAGAAAAAGGGCAACACACCATAAGTGTATCGCCCCAATGAGCC
CGTTAAAAAGACGGTGGCT

Structures

Antitoxin