Detailed information of TA system TA057510

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 53213..53472
• Replicon: chromosome
• Accession: NZ_CP012968
• Organism: Staphylococcus sp. AntiMn-1 isolate deep-sea sediment of east Pacific Nodule Province

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: AOB58_RS13255
• Protein ID: WP_002511402.1
• Coordinates: 53213..53320 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF1
Locus tag	-
Coordinates	53310..53472 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AOB58_RS00240	48447..49319	+	873	WP_002507156.1	ABC transporter ATP-binding protein	-
AOB58_RS00245	49319..50047	+	729	WP_002507157.1	ABC transporter permease subunit	-
AOB58_RS00250	50130..50690	-	561	WP_064782803.1	thioredoxin family protein	-
AOB58_RS00255	50905..51318	+	414	WP_203226407.1	hypothetical protein	-
AOB58_RS00260	51439..51999	+	561	WP_002511403.1	DUF1700 domain-containing protein	-
AOB58_RS00265	51996..52847	+	852	WP_021339982.1	DUF4097 family beta strand repeat protein	-
AOB58_RS13255	53213..53320	+	108	WP_002511402.1	putative holin-like toxin	Toxin
-	53310..53472	-	163	NuclAT_0	-	Antitoxin
-	53377..53433	-	57	NuclAT_2	-	-
-	53377..53433	-	57	NuclAT_3	-	-
AOB58_RS13495	53608..53778	-	171	WP_021339983.1	tyrosine-type recombinase/integrase	-
AOB58_RS00270	54086..55126	-	1041	WP_021339984.1	choloylglycine hydrolase	-
AOB58_RS13410	55621..55791	+	171	WP_002507168.1	hypothetical protein	-
AOB58_RS00275	55894..56073	+	180	WP_064782805.1	hypothetical protein	-
AOB58_RS00280	56066..56245	+	180	WP_064782806.1	hypothetical protein	-
AOB58_RS00285	56300..56710	-	411	WP_002507169.1	YolD-like family protein	-
AOB58_RS00290	56887..57924	+	1038	WP_021339833.1	lactonase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (4-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3756.72 Da
• Isoelectric Point: 10.4997

>T57510 WP_002511402.1 NZ_CP012968:53213-53320 [Staphylococcus sp. AntiMn-1]
VVPIVEALHLMLGFGTFIVTLLGLVVAIVKLSHKK

Nucleotide

• Length: 108 bp

>T57510 NZ_CP012968:53213-53320 [Staphylococcus sp. AntiMn-1]
GTGGTTCCAATTGTAGAAGCACTACACTTAATGTTAGGTTTCGGTACTTTCATCGTTACCTTATTAGGTTTAGTGGTTGC
AATTGTTAAATTAAGCCATAAAAAATAA

Antitoxin

Nucleotide

• Length: 163 bp

>AT57510 NZ_CP012968:c53472-53310 [Staphylococcus sp. AntiMn-1]
ATTTGATAATATTTTTATGTTGTGGTAATTTATATATAGAAAAAGGGCAACACACCATAAGTGTATCGCCCTAATGAGCC
CGTTAAAAAGACGGTGGCTGGAATTTAATAATGATTAAATAATCATCTCATCCTCGCCAAAGTTAGAGATGGTTATTTTT
TAT

Structures

Antitoxin