Detailed information of TA system TA057481

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): higBA (relBE)/HigB-HigA
• Location: 334341..334930
• Replicon: chromosome
• Accession: NZ_CP012947
• Organism: Xanthomonas oryzae pv. oryzae strain PXO83

Toxin (Protein)

• Gene name: graT
• Uniprot ID: A0A8E2YMU3
• Locus tag: APZ20_RS01460
• Protein ID: WP_011260747.1
• Coordinates: 334341..334622 (+)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: higA
• Uniprot ID: -
• Locus tag: APZ20_RS01465
• Protein ID: WP_011260746.1
• Coordinates: 334640..334930 (+)
• Length: 97 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
APZ20_RS01455	331994..334246	+	2253	WP_044756263.1	exodeoxyribonuclease V subunit alpha	-
APZ20_RS01460	334341..334622	+	282	WP_011260747.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
APZ20_RS01465	334640..334930	+	291	WP_011260746.1	HigA family addiction module antidote protein	Antitoxin
APZ20_RS01470	335869..337263	+	1395	WP_011260745.1	nucleoside hydrolase	-
APZ20_RS01475	337713..338045	-	333	WP_011260743.1	hypothetical protein	-
APZ20_RS01485	338381..338605	+	225	WP_044756265.1	hypothetical protein	-
APZ20_RS01490	338743..339177	+	435	WP_011260742.1	PAAR domain-containing protein	-
APZ20_RS01495	339180..339656	+	477	WP_011260741.1	DUF4123 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-1 (4-93)

Antitoxin

• Cro/C1-type helix-turn-helix domain (14-68)

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 11038.77 Da
• Isoelectric Point: 10.2139

>T57481 WP_011260747.1 NZ_CP012947:334341-334622 [Xanthomonas oryzae pv. oryzae]
VIRSFIDKDAEKIWLGERSRRLPADIQLVARRKLRMLNAAAHLDDLRIPPANRLEALKGQQRGQYSIRINDQWRICFRWM
EGDVVQVEIVDYH

Nucleotide

• Length: 282 bp

>T57481 NZ_CP012947:334341-334622 [Xanthomonas oryzae pv. oryzae]
GTGATCAGGAGCTTTATCGACAAGGACGCCGAAAAGATCTGGCTGGGTGAGCGTTCCCGCCGGTTGCCTGCCGACATCCA
ATTGGTCGCGCGCCGCAAGTTGCGCATGCTCAATGCCGCCGCGCATCTCGACGATCTGCGGATCCCGCCCGCCAACCGGC
TGGAAGCGTTGAAGGGCCAGCAGCGCGGCCAGTACAGCATCCGGATCAACGATCAATGGCGCATCTGCTTCCGATGGATG
GAAGGCGATGTGGTCCAGGTCGAAATCGTCGATTACCACTGA

Antitoxin

Protein

• Length: 97 a.a.
• Molecular weight: 10420.07 Da
• Isoelectric Point: 7.2040

>AT57481 WP_011260746.1 NZ_CP012947:334640-334930 [Xanthomonas oryzae pv. oryzae]
MTVLPNIHPGDILLEEFLEPLGISQNALARATGVPPRRINEIVLGKRGITADTAVRLAAALGTSERFWLGLQADYELEQA
HRALGDLPARIKRLAA

Nucleotide

• Length: 291 bp

>AT57481 NZ_CP012947:334640-334930 [Xanthomonas oryzae pv. oryzae]
ATGACGGTCCTACCCAATATCCATCCTGGCGACATTCTGCTTGAGGAGTTTCTCGAGCCTCTGGGCATCAGCCAGAACGC
ACTGGCACGCGCCACCGGCGTCCCGCCGCGCCGTATCAACGAAATCGTGCTGGGCAAGCGCGGCATCACTGCCGACACTG
CCGTGCGTCTGGCCGCCGCGTTGGGCACCTCCGAGCGCTTCTGGCTGGGCCTGCAGGCCGACTACGAGCTGGAACAGGCG
CATCGCGCGCTGGGCGATTTGCCGGCACGGATCAAGCGGCTGGCGGCGTGA