Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 941453..941675 Replicon chromosome
Accession NZ_CP012869
Organism Escherichia coli strain K-12 substr. MG1655_TMP32XR1

Toxin (Protein)


Gene name ldrD Uniprot ID S1E8T8
Locus tag QR62_RS04610 Protein ID WP_000141634.1
Coordinates 941568..941675 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 941453..941519 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QR62_RS04585 936894..937796 + 903 WP_000084677.1 dipeptide ABC transporter permease DppC -
QR62_RS04590 937807..938790 + 984 WP_001196486.1 dipeptide ABC transporter ATP-binding protein -
QR62_RS04595 938787..939791 + 1005 WP_000107012.1 dipeptide ABC transporter ATP-binding subunit DppF -
QR62_RS04600 939821..941092 - 1272 WP_001295225.1 transporter -
- 941453..941519 - 67 - - Antitoxin
QR62_RS04610 941568..941675 + 108 WP_000141634.1 type I toxin-antitoxin system toxic polypeptide LdrD Toxin
QR62_RS04615 941762..943441 - 1680 WP_000191622.1 cellulose biosynthesis protein BcsG -
QR62_RS04620 943438..943629 - 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
QR62_RS04625 943626..945197 - 1572 WP_001204931.1 cellulose biosynthesis protein BcsE -
QR62_RS04630 945470..945658 + 189 WP_001063318.1 YhjR family protein -
QR62_RS04635 945670..946422 + 753 Protein_852 cellulose biosynthesis protein BcsQ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3916.72 Da        Isoelectric Point: 9.0157

>T57320 WP_000141634.1 NZ_CP012869:941568-941675 [Escherichia coli]
MTFAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T57320 NZ_CP012869:941568-941675 [Escherichia coli]
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 67 bp

>AT57320 NZ_CP012869:c941519-941453 [Escherichia coli]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 5LBJ

Antitoxin

Download structure file

References