57204

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 1046057..1046241 Replicon chromosome
Accession NZ_CP012756
Organism Staphylococcus aureus strain JS395

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag ACH32_RS05575 Protein ID WP_000482647.1
Coordinates 1046134..1046241 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 1046057..1046117 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ACH32_RS05555 1041643..1041810 - 168 WP_031785511.1 hypothetical protein -
ACH32_RS05565 1042041..1043774 - 1734 WP_000488492.1 ABC transporter ATP-binding protein/permease -
ACH32_RS05570 1043823..1045562 - 1740 WP_001064832.1 ABC transporter ATP-binding protein/permease -
- 1046057..1046117 + 61 - - Antitoxin
ACH32_RS05575 1046134..1046241 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
ACH32_RS05580 1046375..1046761 - 387 WP_000779354.1 flippase GtxA -
ACH32_RS05585 1047029..1048171 + 1143 WP_001176872.1 glycerate kinase -
ACH32_RS05590 1048231..1048890 + 660 WP_060649688.1 hypothetical protein -
ACH32_RS05595 1049070..1050281 + 1212 WP_001191973.1 multidrug effflux MFS transporter -
ACH32_RS05600 1050404..1050877 - 474 WP_000456490.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - sbi / hlgA / hlgA / hlgC / hlgB 1030943..1046761 15818


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T57204 WP_000482647.1 NZ_CP012756:c1046241-1046134 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T57204 NZ_CP012756:c1046241-1046134 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT57204 NZ_CP012756:1046057-1046117 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAAGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References