Detailed information of TA system TA057199

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-SprF1/-
• Location: 533423..533730
• Replicon: chromosome
• Accession: NZ_CP012756
• Organism: Staphylococcus aureus strain JS395

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: ACH32_RS14535
• Protein ID: WP_078159559.1
• Coordinates: 533554..533730 (-)
• Length: 59 a.a.

Antitoxin (RNA)

Gene name	SprF1
Locus tag	-
Coordinates	533423..533562 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ACH32_RS02820	528763..529023	+	261	WP_001791826.1	hypothetical protein	-
ACH32_RS02825	529076..529426	-	351	WP_000702262.1	complement inhibitor SCIN-A	-
ACH32_RS02830	530110..530559	+	450	WP_000727645.1	chemotaxis-inhibiting protein CHIPS	-
ACH32_RS02835	530654..530988	-	335	Protein_514	SH3 domain-containing protein	-
ACH32_RS02840	531639..532130	-	492	WP_000920042.1	staphylokinase	-
ACH32_RS02845	532321..533076	-	756	WP_000861027.1	CHAP domain-containing protein	-
ACH32_RS02850	533088..533342	-	255	WP_000611512.1	phage holin	-
ACH32_RS02855	533394..533501	+	108	WP_001791821.1	hypothetical protein	-
-	533423..533562	+	140	NuclAT_0	-	Antitoxin
-	533423..533562	+	140	NuclAT_0	-	Antitoxin
-	533423..533562	+	140	NuclAT_0	-	Antitoxin
-	533423..533562	+	140	NuclAT_0	-	Antitoxin
ACH32_RS14535	533554..533730	-	177	WP_078159559.1	putative holin-like toxin	Toxin
ACH32_RS02860	533873..534247	-	375	WP_060649626.1	hypothetical protein	-
ACH32_RS02865	534281..534565	-	285	WP_000400415.1	hypothetical protein	-
ACH32_RS15375	534609..534776	-	168	WP_000421095.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (30-58)

Sequences

Toxin

Protein

• Length: 59 a.a.
• Molecular weight: 6821.39 Da
• Isoelectric Point: 10.6777

>T57199 WP_078159559.1 NZ_CP012756:c533730-533554 [Staphylococcus aureus]
MDRWWLSEYKEVVPMAALLKSLERRRLMITISTMLQFGLFLIALIGIVIKLIELSNKK

Nucleotide

• Length: 177 bp

>T57199 NZ_CP012756:c533730-533554 [Staphylococcus aureus]
TTGGATAGATGGTGGCTATCTGAGTATAAGGAGGTGGTGCCTATGGCGGCATTACTGAAATCTTTAGAAAGGAGACGCCT
AATGATTACAATTAGTACCATGTTGCAGTTTGGTTTATTCCTTATTGCATTGATAGGTATAGTAATCAAGCTTATTGAAT
TAAGCAATAAAAAATAA

Antitoxin

Nucleotide

• Length: 140 bp

>AT57199 NZ_CP012756:533423-533562 [Staphylococcus aureus]
ATATATAGAAAAAGGGCAACATGCGCAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGGCTATTTTAGATTAAA
GATTAAATTAATAACCATTTAACCATCGAAACCAGCCAAAGTTAGCGATGGTTATTTTTT

Structures

Antitoxin