Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 4020696..4020954 Replicon chromosome
Accession NZ_CP012635
Organism Escherichia coli strain SF-088

Toxin (Protein)


Gene name hokC Uniprot ID S1NX00
Locus tag AN203_RS20095 Protein ID WP_000809168.1
Coordinates 4020802..4020954 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 4020696..4020753 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AN203_RS20080 4016528..4017787 - 1260 WP_000494924.1 hypothetical protein -
AN203_RS20085 4017916..4019409 - 1494 WP_001350775.1 sulfatase-like hydrolase/transferase -
AN203_RS20090 4019429..4020190 - 762 WP_001274823.1 hypothetical protein -
- 4020696..4020753 - 58 - - Antitoxin
AN203_RS20095 4020802..4020954 + 153 WP_000809168.1 type I toxin-antitoxin system toxin MokC Toxin
AN203_RS20100 4021059..4022189 - 1131 WP_001118464.1 molecular chaperone DnaJ -
AN203_RS20105 4022278..4024194 - 1917 WP_000516135.1 molecular chaperone DnaK -
AN203_RS20110 4024566..4024970 + 405 WP_000843687.1 DUF2541 family protein -
AN203_RS20115 4024996..4025709 + 714 WP_001102393.1 acidic protein MsyB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T56893 WP_000809168.1 NZ_CP012635:4020802-4020954 [Escherichia coli]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

>T56893 NZ_CP012635:4020802-4020954 [Escherichia coli]
ATGAAGCAGCATAAGGCGATGATTGTCGCCCTGATCGTCATCTGTATCACCGCCGTAGTGGCGGCGCTGGTAACGAGAAA
AGACCTCTGTGAGGTTCACATCCGAACTGGCCAGACGGAGGTTGCTGTTTTCACGGCTTACGAATCCGAGTAA

Antitoxin


Download         Length: 58 bp

>AT56893 NZ_CP012635:c4020753-4020696 [Escherichia coli]
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1NX00

Antitoxin

Download structure file

References