Detailed information of TA system TA056436

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2179377..2179640
• Replicon: chromosome
• Accession: NZ_CP012409
• Organism: Staphylococcus aureus subsp. aureus Tager 104

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: -
• Locus tag: Tgr_RS10780
• Protein ID: WP_078064523.1
• Coordinates: 2179377..2179481 (+)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF2
Locus tag	-
Coordinates	2179476..2179640 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
Tgr_RS10750	2174566..2174850	-	285	WP_000134547.1	hypothetical protein	-
Tgr_RS10755	2174890..2175546	+	657	Protein_2057	ATP-binding cassette domain-containing protein	-
Tgr_RS10760	2175614..2176471	+	858	WP_029753951.1	Cof-type HAD-IIB family hydrolase	-
Tgr_RS10765	2177173..2177265	-	93	WP_031844941.1	hypothetical protein	-
Tgr_RS10770	2177554..2178690	+	1137	WP_000115566.1	SAP domain-containing protein	-
Tgr_RS15290	2178733..2179216	+	484	Protein_2061	recombinase family protein	-
Tgr_RS10780	2179377..2179481	+	105	WP_078064523.1	hypothetical protein	Toxin
-	2179476..2179640	-	165	-	-	Antitoxin
Tgr_RS10785	2179988..2181079	-	1092	WP_000495687.1	hypothetical protein	-
Tgr_RS10790	2181345..2182325	-	981	WP_000019746.1	CDF family zinc efflux transporter CzrB	-
Tgr_RS10795	2182327..2182647	-	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
Tgr_RS10800	2182799..2183464	+	666	WP_001024086.1	SDR family oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3906.77 Da
• Isoelectric Point: 5.5724

>T56436 WP_078064523.1 NZ_CP012409:2179377-2179481 [Staphylococcus aureus subsp. aureus Tager 104]
MLILERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T56436 NZ_CP012409:2179377-2179481 [Staphylococcus aureus subsp. aureus Tager 104]
TTGTTAATCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin

Nucleotide

• Length: 165 bp

>AT56436 NZ_CP012409:c2179640-2179476 [Staphylococcus aureus subsp. aureus Tager 104]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Structures

Antitoxin