Detailed information of TA system TA056433

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-SprA2AS/-
• Location: 1880466..1880650
• Replicon: chromosome
• Accession: NZ_CP012409
• Organism: Staphylococcus aureus subsp. aureus Tager 104

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: A0A2P7CQJ7
• Locus tag: Tgr_RS09205
• Protein ID: WP_000482647.1
• Coordinates: 1880466..1880573 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	1880590..1880650 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
Tgr_RS09180	1875827..1876300	+	474	WP_000456493.1	GyrI-like domain-containing protein	-
Tgr_RS09185	1876423..1877634	-	1212	WP_001191923.1	multidrug effflux MFS transporter	-
Tgr_RS09190	1877817..1878476	-	660	WP_000831298.1	membrane protein	-
Tgr_RS09195	1878536..1879678	-	1143	WP_001176863.1	glycerate kinase	-
Tgr_RS09200	1879946..1880332	+	387	WP_000779352.1	flippase GtxA	-
Tgr_RS09205	1880466..1880573	+	108	WP_000482647.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	1880590..1880650	-	61	-	-	Antitoxin
Tgr_RS15355	1880600..1880767	+	168	WP_000301893.1	hypothetical protein	-
Tgr_RS09210	1881296..1883059	+	1764	WP_001064819.1	ABC transporter ATP-binding protein/permease	-
Tgr_RS09215	1883084..1884815	+	1732	Protein_1764	ABC transporter ATP-binding protein	-
Tgr_RS09225	1885046..1885213	+	168	WP_001789205.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 4012.76 Da
• Isoelectric Point: 10.4935

>T56433 WP_000482647.1 NZ_CP012409:1880466-1880573 [Staphylococcus aureus subsp. aureus Tager 104]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Nucleotide

• Length: 108 bp

>T56433 NZ_CP012409:1880466-1880573 [Staphylococcus aureus subsp. aureus Tager 104]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin

Nucleotide

• Length: 61 bp

>AT56433 NZ_CP012409:c1880650-1880590 [Staphylococcus aureus subsp. aureus Tager 104]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Structures

Toxin

• AlphaFold DB: A0A2P7CQJ7

Antitoxin