Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 3676022..3676244 Replicon chromosome
Accession NZ_CP012126
Organism Escherichia coli strain DH1Ec104

Toxin (Protein)


Gene name ldrD Uniprot ID S1E8T8
Locus tag ADZ27_RS18130 Protein ID WP_000141634.1
Coordinates 3676022..3676129 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 3676178..3676244 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ADZ27_RS18105 3671275..3672027 - 753 Protein_3464 cellulose biosynthesis protein BcsQ -
ADZ27_RS18110 3672039..3672227 - 189 WP_001063318.1 YhjR family protein -
ADZ27_RS18115 3672500..3674071 + 1572 WP_001204931.1 cellulose biosynthesis protein BcsE -
ADZ27_RS18120 3674068..3674259 + 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
ADZ27_RS18125 3674256..3675935 + 1680 WP_000191622.1 cellulose biosynthesis protein BcsG -
ADZ27_RS18130 3676022..3676129 - 108 WP_000141634.1 type I toxin-antitoxin system toxic polypeptide LdrD Toxin
- 3676178..3676244 + 67 - - Antitoxin
ADZ27_RS18140 3676605..3677876 + 1272 WP_001295225.1 transporter -
ADZ27_RS18145 3677906..3678910 - 1005 WP_000107012.1 dipeptide ABC transporter ATP-binding subunit DppF -
ADZ27_RS18150 3678907..3679890 - 984 WP_001196486.1 dipeptide ABC transporter ATP-binding protein -
ADZ27_RS18155 3679901..3680803 - 903 WP_000084677.1 dipeptide ABC transporter permease DppC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3916.72 Da        Isoelectric Point: 9.0157

>T55901 WP_000141634.1 NZ_CP012126:c3676129-3676022 [Escherichia coli]
MTFAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T55901 NZ_CP012126:c3676129-3676022 [Escherichia coli]
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 67 bp

>AT55901 NZ_CP012126:3676178-3676244 [Escherichia coli]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 5LBJ

Antitoxin

Download structure file

References