55858

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 3677890..3678112 Replicon chromosome
Accession NZ_CP012125
Organism Escherichia coli strain DH1Ec095

Toxin (Protein)


Gene name ldrD Uniprot ID S1E8T8
Locus tag ADS71_RS18135 Protein ID WP_000141634.1
Coordinates 3677890..3677997 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 3678046..3678112 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ADS71_RS18110 3673143..3673895 - 753 Protein_3465 cellulose biosynthesis protein BcsQ -
ADS71_RS18115 3673907..3674095 - 189 WP_001063318.1 YhjR family protein -
ADS71_RS18120 3674368..3675939 + 1572 WP_001204931.1 cellulose biosynthesis protein BcsE -
ADS71_RS18125 3675936..3676127 + 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
ADS71_RS18130 3676124..3677803 + 1680 WP_000191622.1 cellulose biosynthesis protein BcsG -
ADS71_RS18135 3677890..3677997 - 108 WP_000141634.1 type I toxin-antitoxin system toxic polypeptide LdrD Toxin
- 3678046..3678112 + 67 - - Antitoxin
ADS71_RS18145 3678473..3679744 + 1272 WP_001295225.1 transporter -
ADS71_RS18150 3679774..3680778 - 1005 WP_000107012.1 dipeptide ABC transporter ATP-binding subunit DppF -
ADS71_RS18155 3680775..3681758 - 984 WP_001196486.1 dipeptide ABC transporter ATP-binding protein -
ADS71_RS18160 3681769..3682671 - 903 WP_000084677.1 dipeptide ABC transporter permease DppC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3916.72 Da        Isoelectric Point: 9.0157

>T55858 WP_000141634.1 NZ_CP012125:c3677997-3677890 [Escherichia coli]
MTFAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T55858 NZ_CP012125:c3677997-3677890 [Escherichia coli]
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 67 bp

>AT55858 NZ_CP012125:3678046-3678112 [Escherichia coli]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 5LBJ

Antitoxin

Download structure file

References