Detailed information of TA system TA055822

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 2314761..2314943
• Replicon: chromosome
• Accession: NZ_CP012120
• Organism: Staphylococcus aureus strain USA300_2014.C02

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: ACO02_RS15410
• Protein ID: WP_001801861.1
• Coordinates: 2314848..2314943 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	2314761..2314820 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ACO02_RS12240	2313899..2314276	+	378	WP_001037045.1	DUF1433 domain-containing protein	-
ACO02_RS12245	2314470..2314646	+	177	Protein_2254	transposase	-
ACO02_RS12250	2314624..2314725	-	102	WP_001791893.1	hypothetical protein	-
-	2314761..2314820	+	60	-	-	Antitoxin
ACO02_RS15410	2314848..2314943	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
ACO02_RS12260	2315146..2315289	+	144	WP_001549059.1	transposase	-
ACO02_RS12270	2315893..2316276	+	384	WP_000070811.1	hypothetical protein	-
ACO02_RS12275	2316287..2316463	+	177	WP_000375476.1	hypothetical protein	-
ACO02_RS12280	2316465..2316650	+	186	WP_000809857.1	hypothetical protein	-
ACO02_RS12285	2316764..2317405	+	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
ACO02_RS12290	2317623..2318174	-	552	WP_000414205.1	hypothetical protein	-
ACO02_RS12295	2318272..2318616	-	345	WP_000627551.1	DUF3969 family protein	-
ACO02_RS12300	2318657..2319283	-	627	Protein_2264	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	hlgA / lukD	2281672..2352396	70724

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T55822 WP_001801861.1 NZ_CP012120:c2314943-2314848 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T55822 NZ_CP012120:c2314943-2314848 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT55822 NZ_CP012120:2314761-2314820 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin