Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 1979070..1979333 Replicon chromosome
Accession NZ_CP012120
Organism Staphylococcus aureus strain USA300_2014.C02

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag ACO02_RS10165 Protein ID WP_001802298.1
Coordinates 1979070..1979174 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 1979169..1979333 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ACO02_RS10140 1974454..1975236 + 783 WP_000908176.1 ABC transporter ATP-binding protein -
ACO02_RS10145 1975304..1976161 + 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
ACO02_RS10150 1976866..1976958 - 93 WP_001790138.1 hypothetical protein -
ACO02_RS10155 1977247..1978383 + 1137 WP_000115564.1 SAP domain-containing protein -
ACO02_RS15400 1978426..1978909 + 484 Protein_1903 recombinase family protein -
ACO02_RS10165 1979070..1979174 + 105 WP_001802298.1 hypothetical protein Toxin
- 1979169..1979333 - 165 - - Antitoxin
ACO02_RS10170 1979674..1980765 - 1092 WP_000495671.1 lytic regulatory protein -
ACO02_RS10175 1981031..1982011 - 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
ACO02_RS10180 1982013..1982333 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
ACO02_RS10185 1982485..1983150 + 666 WP_001024094.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T55812 WP_001802298.1 NZ_CP012120:1979070-1979174 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T55812 NZ_CP012120:1979070-1979174 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
CAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT55812 NZ_CP012120:c1979333-1979169 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References