Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1038147..1038329 Replicon chromosome
Accession NZ_CP012119
Organism Staphylococcus aureus strain USA300_2014.C01

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag AC807_RS15640 Protein ID WP_001801861.1
Coordinates 1038147..1038242 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1038270..1038329 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AC807_RS05405 1033807..1034433 + 627 Protein_1001 hypothetical protein -
AC807_RS05410 1034474..1034818 + 345 WP_000627551.1 DUF3969 family protein -
AC807_RS05415 1034916..1035467 + 552 WP_000414205.1 hypothetical protein -
AC807_RS05420 1035685..1036326 - 642 WP_000494956.1 ImmA/IrrE family metallo-endopeptidase -
AC807_RS05425 1036440..1036625 - 186 WP_000809857.1 hypothetical protein -
AC807_RS05430 1036627..1036803 - 177 WP_000375476.1 hypothetical protein -
AC807_RS05435 1036814..1037197 - 384 WP_000070811.1 hypothetical protein -
AC807_RS05445 1037801..1037944 - 144 WP_001549059.1 transposase -
AC807_RS15640 1038147..1038242 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1038270..1038329 - 60 - - Antitoxin
AC807_RS05455 1038365..1038466 + 102 WP_001791893.1 hypothetical protein -
AC807_RS05460 1038444..1038620 - 177 Protein_1011 transposase -
AC807_RS05465 1038814..1039191 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1031247..1056848 25601


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T55789 WP_001801861.1 NZ_CP012119:1038147-1038242 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T55789 NZ_CP012119:1038147-1038242 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 60 bp

>AT55789 NZ_CP012119:c1038329-1038270 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References