Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 110824..111476 Replicon chromosome
Accession NZ_CP012046
Organism Achromobacter xylosoxidans strain MN001

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag Axylo_RS00450 Protein ID WP_049070435.1
Coordinates 110824..111162 (+) Length 113 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag Axylo_RS00455 Protein ID WP_020925696.1
Coordinates 111159..111476 (+) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Axylo_RS26420 105833..107074 - 1242 WP_080977285.1 hypothetical protein -
Axylo_RS00425 107763..108095 + 333 WP_049070429.1 hypothetical protein -
Axylo_RS00430 108190..109146 - 957 WP_049070431.1 helix-turn-helix domain-containing protein -
Axylo_RS00435 109285..109596 + 312 WP_049070432.1 DUF3817 domain-containing protein -
Axylo_RS00440 109600..110028 + 429 WP_049070433.1 CopD family protein -
Axylo_RS26365 110088..110594 - 507 WP_020925698.1 hypothetical protein -
Axylo_RS00450 110824..111162 + 339 WP_049070435.1 hypothetical protein Toxin
Axylo_RS00455 111159..111476 + 318 WP_020925696.1 transcriptional regulator Antitoxin
Axylo_RS00460 111614..112039 + 426 WP_049070437.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(43-102)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 13233.17 Da        Isoelectric Point: 10.0510

>T55559 WP_049070435.1 NZ_CP012046:110824-111162 [Achromobacter xylosoxidans]
MKAVFVELPAFARHRGDYLDDDDFRLLQQAMMWRPDAGAVIEGTGGLRKMRFGDPRRGKGKRGGLRVIYYWWDGREQFWL
FSLYDKDEVSDLSAREKRMLKGMLDAEREARR

Download         Length: 339 bp

>T55559 NZ_CP012046:110824-111162 [Achromobacter xylosoxidans]
ATGAAAGCTGTATTCGTCGAACTACCCGCGTTTGCTCGTCACCGAGGAGACTATCTTGATGACGACGACTTTCGTCTCCT
GCAGCAAGCCATGATGTGGCGTCCTGACGCCGGCGCCGTCATCGAAGGGACAGGAGGGCTACGAAAAATGCGTTTTGGCG
ATCCCCGCCGCGGCAAGGGTAAGCGCGGCGGTTTGCGTGTCATCTACTACTGGTGGGACGGTCGGGAACAGTTTTGGTTG
TTCTCGTTGTATGACAAGGATGAAGTCAGCGATTTGAGCGCCCGGGAAAAGAGGATGCTCAAGGGCATGTTGGACGCGGA
ACGTGAGGCACGGCGATGA

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 12102.95 Da        Isoelectric Point: 10.3044

>AT55559 WP_020925696.1 NZ_CP012046:111159-111476 [Achromobacter xylosoxidans]
MKKKRNLYAEIAEGFDALAAEREGKRTLRTHKVEMNPAPDLTAEELLAIRERLHLSRQVFAHYLRTNPRTLENWEQGRAK
PNAQAALLIRLVEKFPDTVERLAAV

Download         Length: 318 bp

>AT55559 NZ_CP012046:111159-111476 [Achromobacter xylosoxidans]
ATGAAAAAAAAGCGAAACCTGTATGCGGAAATCGCCGAAGGCTTTGATGCGCTTGCGGCTGAGCGTGAGGGCAAACGAAC
GCTGCGTACGCACAAAGTGGAAATGAATCCTGCGCCTGATCTGACCGCCGAGGAACTCCTGGCCATACGCGAGCGTTTGC
ATCTGTCACGGCAGGTGTTCGCGCACTATCTGCGCACCAACCCCCGCACTCTCGAAAACTGGGAACAGGGCCGCGCCAAG
CCAAATGCGCAGGCCGCCTTGCTGATTCGGCTGGTCGAGAAGTTTCCCGACACCGTGGAGCGATTGGCGGCGGTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References