Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2357149..2357366 Replicon chromosome
Accession NZ_CP012018
Organism Staphylococcus aureus strain Gv88

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag SAGV88_RS12200 Protein ID WP_001802298.1
Coordinates 2357262..2357366 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2357149..2357204 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAGV88_RS12180 2353286..2353951 - 666 WP_001024094.1 SDR family oxidoreductase -
SAGV88_RS12185 2354103..2354423 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
SAGV88_RS12190 2354425..2355405 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
SAGV88_RS12195 2355671..2356762 + 1092 WP_000495671.1 lytic regulatory protein -
- 2357149..2357204 + 56 - - Antitoxin
SAGV88_RS12200 2357262..2357366 - 105 WP_001802298.1 hypothetical protein Toxin
SAGV88_RS16395 2357527..2358010 - 484 Protein_2327 recombinase family protein -
SAGV88_RS12210 2358053..2359189 - 1137 WP_000115564.1 SAP domain-containing protein -
SAGV88_RS12215 2359478..2359570 + 93 WP_001790138.1 hypothetical protein -
SAGV88_RS12220 2360275..2361132 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
SAGV88_RS12225 2361200..2361982 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T55527 WP_001802298.1 NZ_CP012018:c2357366-2357262 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T55527 NZ_CP012018:c2357366-2357262 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT55527 NZ_CP012018:2357149-2357204 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References