Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2358175..2358392 Replicon chromosome
Accession NZ_CP012015
Organism Staphylococcus aureus strain Gv51

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag SAGV51_RS12180 Protein ID WP_001802298.1
Coordinates 2358288..2358392 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2358175..2358230 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAGV51_RS12160 2354312..2354977 - 666 WP_001024094.1 SDR family oxidoreductase -
SAGV51_RS12165 2355129..2355449 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
SAGV51_RS12170 2355451..2356431 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
SAGV51_RS12175 2356697..2357788 + 1092 WP_000495671.1 lytic regulatory protein -
- 2358175..2358230 + 56 - - Antitoxin
SAGV51_RS12180 2358288..2358392 - 105 WP_001802298.1 hypothetical protein Toxin
SAGV51_RS16400 2358553..2359036 - 484 Protein_2326 recombinase family protein -
SAGV51_RS12190 2359079..2360215 - 1137 WP_000115564.1 SAP domain-containing protein -
SAGV51_RS12195 2360504..2360596 + 93 WP_001790138.1 hypothetical protein -
SAGV51_RS12200 2361301..2362158 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
SAGV51_RS12205 2362226..2363008 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T55503 WP_001802298.1 NZ_CP012015:c2358392-2358288 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T55503 NZ_CP012015:c2358392-2358288 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT55503 NZ_CP012015:2358175-2358230 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References