Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2366253..2366516 Replicon chromosome
Accession NZ_CP012013
Organism Staphylococcus aureus strain Be62

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag SABE62_RS12205 Protein ID WP_001802298.1
Coordinates 2366412..2366516 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2366253..2366417 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SABE62_RS12185 2362436..2363101 - 666 WP_001024094.1 SDR family oxidoreductase -
SABE62_RS12190 2363253..2363573 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
SABE62_RS12195 2363575..2364555 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
SABE62_RS12200 2364821..2365912 + 1092 WP_000495671.1 lytic regulatory protein -
- 2366253..2366417 + 165 - - Antitoxin
SABE62_RS12205 2366412..2366516 - 105 WP_001802298.1 hypothetical protein Toxin
SABE62_RS16425 2366677..2367160 - 484 Protein_2329 recombinase family protein -
SABE62_RS12215 2367203..2368339 - 1137 WP_000115564.1 SAP domain-containing protein -
SABE62_RS12220 2368628..2368720 + 93 WP_001790138.1 hypothetical protein -
SABE62_RS12225 2369425..2370282 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
SABE62_RS12230 2370350..2371132 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T55481 WP_001802298.1 NZ_CP012013:c2366516-2366412 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T55481 NZ_CP012013:c2366516-2366412 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT55481 NZ_CP012013:2366253-2366417 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References