Detailed information of TA system TA055470

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 2025233..2025415
• Replicon: chromosome
• Accession: NZ_CP012013
• Organism: Staphylococcus aureus strain Be62

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: SABE62_RS16390
• Protein ID: WP_001801861.1
• Coordinates: 2025233..2025328 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	2025356..2025415 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SABE62_RS10130	2020893..2021519	+	627	WP_000669046.1	hypothetical protein	-
SABE62_RS10135	2021560..2021904	+	345	WP_000627551.1	DUF3969 family protein	-
SABE62_RS10140	2022002..2022553	+	552	WP_000414205.1	hypothetical protein	-
SABE62_RS10145	2022771..2023412	-	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
SABE62_RS10150	2023526..2023711	-	186	WP_000809857.1	hypothetical protein	-
SABE62_RS10155	2023713..2023889	-	177	WP_000375476.1	hypothetical protein	-
SABE62_RS10160	2023900..2024283	-	384	WP_000070811.1	hypothetical protein	-
SABE62_RS10170	2024887..2025030	-	144	WP_001549059.1	transposase	-
SABE62_RS16390	2025233..2025328	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	2025356..2025415	-	60	-	-	Antitoxin
SABE62_RS10175	2025451..2025552	+	102	WP_001791893.1	hypothetical protein	-
SABE62_RS15970	2025530..2025706	-	177	Protein_1972	transposase	-
SABE62_RS10180	2025900..2026277	-	378	WP_001037045.1	DUF1433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-83)

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T55470 WP_001801861.1 NZ_CP012013:2025233-2025328 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T55470 NZ_CP012013:2025233-2025328 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT55470 NZ_CP012013:c2025415-2025356 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin