Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4580953..4581314 Replicon chromosome
Accession NZ_CP011962
Organism Xanthomonas oryzae pv. oryzicola strain CFBP2286

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag ACU11_RS19980 Protein ID WP_011257368.1
Coordinates 4580953..4581087 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag ACU11_RS19985 Protein ID WP_011407410.1
Coordinates 4581162..4581314 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ACU11_RS19965 4577966..4578988 - 1023 WP_071162327.1 MBL fold metallo-hydrolase -
ACU11_RS19970 4579041..4580330 - 1290 WP_014505029.1 tryptophan--tRNA ligase -
ACU11_RS19975 4580499..4580708 - 210 WP_011407411.1 CsbD family protein -
ACU11_RS19980 4580953..4581087 - 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
ACU11_RS19985 4581162..4581314 - 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
ACU11_RS19990 4581422..4582345 - 924 WP_014505030.1 arginase -
ACU11_RS19995 4582667..4583275 + 609 WP_014505031.1 hypothetical protein -
ACU11_RS20000 4583272..4583508 + 237 Protein_3947 GTPase -
ACU11_RS20005 4583518..4583810 + 293 Protein_3948 hypothetical protein -
ACU11_RS20010 4584290..4584973 + 684 WP_014505034.1 dTMP kinase -
ACU11_RS20015 4585235..4586203 - 969 WP_014501311.1 IS5-like element ISXo1 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
flank IS/Tn - - 4585235..4586203 968


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T55276 WP_011257368.1 NZ_CP011962:c4581087-4580953 [Xanthomonas oryzae pv. oryzicola]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T55276 NZ_CP011962:c4581087-4580953 [Xanthomonas oryzae pv. oryzicola]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT55276 WP_011407410.1 NZ_CP011962:c4581314-4581162 [Xanthomonas oryzae pv. oryzicola]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT55276 NZ_CP011962:c4581314-4581162 [Xanthomonas oryzae pv. oryzicola]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References