26409

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4444794..4445155 Replicon chromosome
Accession NC_017267
Organism Xanthomonas oryzae pv. oryzicola BLS256

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag XOC_RS19200 Protein ID WP_011257368.1
Coordinates 4444794..4444928 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag XOC_RS19205 Protein ID WP_011407410.1
Coordinates 4445003..4445155 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XOC_RS19185 (XOC_4299) 4441807..4442829 - 1023 WP_071162327.1 MBL fold metallo-hydrolase -
XOC_RS19190 (XOC_4300) 4442882..4444171 - 1290 WP_014505029.1 tryptophan--tRNA ligase -
XOC_RS19195 (XOC_4301) 4444340..4444549 - 210 WP_011407411.1 CsbD family protein -
XOC_RS19200 (XOC_4302) 4444794..4444928 - 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
XOC_RS19205 (XOC_4303) 4445003..4445155 - 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
XOC_RS19210 (XOC_4304) 4445263..4446186 - 924 WP_014505030.1 arginase -
XOC_RS19215 (XOC_4305) 4446508..4447116 + 609 WP_014505031.1 hypothetical protein -
XOC_RS19220 4447113..4447349 + 237 Protein_3782 GTPase -
XOC_RS19225 (XOC_4307) 4447359..4447651 + 293 Protein_3783 hypothetical protein -
XOC_RS19230 (XOC_4308) 4448131..4448814 + 684 WP_014505034.1 dTMP kinase -
XOC_RS19235 (XOC_4309) 4449076..4450044 - 969 WP_014501311.1 IS5-like element ISXo1 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
flank IS/Tn - - 4449076..4450044 968


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T26409 WP_011257368.1 NC_017267:c4444928-4444794 [Xanthomonas oryzae pv. oryzicola BLS256]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T26409 NC_017267:c4444928-4444794 [Xanthomonas oryzae pv. oryzicola BLS256]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT26409 WP_011407410.1 NC_017267:c4445155-4445003 [Xanthomonas oryzae pv. oryzicola BLS256]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT26409 NC_017267:c4445155-4445003 [Xanthomonas oryzae pv. oryzicola BLS256]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References