Detailed information of TA system TA055273

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): higBA (relBE)/HigB-HigA
• Location: 99568..100157
• Replicon: chromosome
• Accession: NZ_CP011962
• Organism: Xanthomonas oryzae pv. oryzicola strain CFBP2286

Toxin (Protein)

• Gene name: graT
• Uniprot ID: G7TIR7
• Locus tag: ACU11_RS00450
• Protein ID: WP_012443754.1
• Coordinates: 99876..100157 (-)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: higA
• Uniprot ID: -
• Locus tag: ACU11_RS00445
• Protein ID: WP_011260746.1
• Coordinates: 99568..99858 (-)
• Length: 97 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ACU11_RS00420	94843..95319	-	477	WP_014501331.1	DUF4123 domain-containing protein	-
ACU11_RS00425	95322..95756	-	435	WP_014501332.1	PAAR domain-containing protein	-
ACU11_RS22020	95872..96117	-	246	WP_041182989.1	hypothetical protein	-
ACU11_RS00435	96453..96785	+	333	WP_011260743.1	hypothetical protein	-
ACU11_RS00440	97236..98630	-	1395	WP_014501334.1	nucleoside hydrolase	-
ACU11_RS00445	99568..99858	-	291	WP_011260746.1	HigA family addiction module antidote protein	Antitoxin
ACU11_RS00450	99876..100157	-	282	WP_012443754.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
ACU11_RS00455	100252..102513	-	2262	WP_014501336.1	exodeoxyribonuclease V subunit alpha	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-1 (1-93)

Antitoxin

• Cro/C1-type helix-turn-helix domain (14-68)

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 11098.89 Da
• Isoelectric Point: 10.5318

>T55273 WP_012443754.1 NZ_CP011962:c100157-99876 [Xanthomonas oryzae pv. oryzicola]
MIRSFIDKDAEKIWLGERSRRLPADIQLVARRKLRMLNAAAHLDDLRIPPANRLEALKGQRRGQYSIRINDQWRICFRWM
EGDVVQVEIVDYH

Nucleotide

• Length: 282 bp

>T55273 NZ_CP011962:c100157-99876 [Xanthomonas oryzae pv. oryzicola]
ATGATCAGGAGCTTTATCGACAAGGACGCCGAAAAGATCTGGCTGGGTGAGCGTTCCCGCCGGTTGCCTGCCGACATCCA
ATTGGTCGCGCGCCGCAAGTTGCGCATGCTCAATGCCGCCGCGCATCTCGACGATCTGCGGATCCCGCCCGCCAACCGGC
TGGAAGCGTTGAAGGGCCAGCGGCGCGGCCAGTACAGCATCCGGATCAACGATCAATGGCGCATCTGCTTCCGATGGATG
GAAGGCGATGTGGTCCAGGTCGAAATCGTCGATTACCACTGA

Antitoxin

Protein

• Length: 97 a.a.
• Molecular weight: 10420.07 Da
• Isoelectric Point: 7.2040

>AT55273 WP_011260746.1 NZ_CP011962:c99858-99568 [Xanthomonas oryzae pv. oryzicola]
MTVLPNIHPGDILLEEFLEPLGISQNALARATGVPPRRINEIVLGKRGITADTAVRLAAALGTSERFWLGLQADYELEQA
HRALGDLPARIKRLAA

Nucleotide

• Length: 291 bp

>AT55273 NZ_CP011962:c99858-99568 [Xanthomonas oryzae pv. oryzicola]
ATGACGGTCCTACCCAATATCCATCCTGGCGACATTCTGCTTGAGGAGTTTCTCGAGCCTCTGGGCATCAGCCAGAACGC
ACTGGCACGCGCCACCGGCGTCCCGCCGCGCCGTATCAACGAAATCGTGCTGGGCAAGCGCGGCATCACTGCCGACACTG
CCGTGCGTCTGGCCGCCGCGTTGGGCACCTCCGAGCGCTTCTGGCTGGGCCTGCAGGCCGACTACGAGCTGGAACAGGCG
CATCGCGCGCTGGGCGATTTGCCGGCACGGATCAAGCGGCTGGCGGCGTGA

Structures

Toxin

• AlphaFold DB: A0A0K0GFW5