Detailed information of TA system TA055261

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): higBA (relBE)/HigB-HigA
• Location: 91738..92327
• Replicon: chromosome
• Accession: NZ_CP011958
• Organism: Xanthomonas oryzae pv. oryzicola strain CFBP7331

Toxin (Protein)

• Gene name: graT
• Uniprot ID: A0A0C5V8F2
• Locus tag: ACU16_RS00415
• Protein ID: WP_024712137.1
• Coordinates: 92046..92327 (-)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: higA
• Uniprot ID: -
• Locus tag: ACU16_RS00410
• Protein ID: WP_011260746.1
• Coordinates: 91738..92028 (-)
• Length: 97 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ACU16_RS00380	87012..87488	-	477	WP_024712141.1	DUF4123 domain-containing protein	-
ACU16_RS00385	87491..87925	-	435	WP_024712140.1	PAAR domain-containing protein	-
ACU16_RS00390	88063..88287	-	225	WP_044751358.1	hypothetical protein	-
ACU16_RS00400	88623..88955	+	333	WP_011260743.1	hypothetical protein	-
ACU16_RS00405	89406..90800	-	1395	WP_024712138.1	nucleoside hydrolase	-
ACU16_RS00410	91738..92028	-	291	WP_011260746.1	HigA family addiction module antidote protein	Antitoxin
ACU16_RS00415	92046..92327	-	282	WP_024712137.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
ACU16_RS00420	92422..94683	-	2262	WP_024712136.1	exodeoxyribonuclease V subunit alpha	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-1 (4-93)

Antitoxin

• Cro/C1-type helix-turn-helix domain (14-68)

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 11125.91 Da
• Isoelectric Point: 10.5318

>T55261 WP_024712137.1 NZ_CP011958:c92327-92046 [Xanthomonas oryzae pv. oryzicola]
MIRSFIDKDAEKIWLGERSRRLPADIQLVARRKLRMLNAAAHLDDLRIPPANRLEALKGQRRGQYNIRINDQWRICFRWM
EGDVVQVEIVDYH

Nucleotide

• Length: 282 bp

>T55261 NZ_CP011958:c92327-92046 [Xanthomonas oryzae pv. oryzicola]
ATGATCAGGAGCTTTATCGACAAGGACGCCGAAAAGATCTGGCTGGGTGAGCGTTCCCGCCGGTTGCCTGCCGACATCCA
ATTGGTCGCGCGCCGCAAGTTGCGCATGCTCAATGCCGCCGCGCATCTCGACGATCTGCGGATCCCGCCCGCCAACCGGC
TGGAAGCGTTGAAGGGCCAGCGGCGCGGCCAGTACAACATCCGGATCAACGATCAATGGCGCATCTGCTTCCGATGGATG
GAAGGCGATGTGGTCCAGGTCGAAATCGTCGATTACCACTGA

Antitoxin

Protein

• Length: 97 a.a.
• Molecular weight: 10420.07 Da
• Isoelectric Point: 7.2040

>AT55261 WP_011260746.1 NZ_CP011958:c92028-91738 [Xanthomonas oryzae pv. oryzicola]
MTVLPNIHPGDILLEEFLEPLGISQNALARATGVPPRRINEIVLGKRGITADTAVRLAAALGTSERFWLGLQADYELEQA
HRALGDLPARIKRLAA

Nucleotide

• Length: 291 bp

>AT55261 NZ_CP011958:c92028-91738 [Xanthomonas oryzae pv. oryzicola]
ATGACGGTCCTACCCAATATCCATCCTGGCGACATTCTGCTTGAGGAGTTTCTCGAGCCTCTGGGCATCAGCCAGAACGC
ACTGGCACGCGCCACCGGCGTCCCGCCGCGCCGTATCAACGAAATCGTGCTGGGCAAGCGCGGCATCACTGCCGACACTG
CCGTGCGTCTGGCCGCCGCGTTGGGCACCTCCGAGCGCTTCTGGCTGGGCCTGCAGGCCGACTACGAGCTGGAACAGGCG
CATCGCGCGCTGGGCGATTTGCCGGCACGGATCAAGCGGCTGGCGGCGTGA

Structures

Toxin

• AlphaFold DB: A0A0C5V8F2