Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 2687284..2688737 Replicon chromosome
Accession NZ_CP011957
Organism Xanthomonas oryzae pv. oryzicola strain BXOR1

Toxin (Protein)


Gene name rlegT Uniprot ID A0A5C2EYQ5
Locus tag ACU15_RS11660 Protein ID WP_047339759.1
Coordinates 2687284..2688135 (-) Length 284 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID A0A0C5V250
Locus tag ACU15_RS11665 Protein ID WP_024710981.1
Coordinates 2688132..2688737 (-) Length 202 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ACU15_RS11630 2682324..2683286 - 963 WP_044751530.1 IS110 family transposase -
ACU15_RS23295 2683511..2683813 - 303 WP_048485513.1 hypothetical protein -
ACU15_RS11645 2684686..2685027 - 342 WP_050585837.1 ParB N-terminal domain-containing protein -
ACU15_RS11650 2685024..2686590 - 1567 Protein_2295 recombinase family protein -
ACU15_RS11655 2686727..2687197 - 471 WP_047339760.1 hypothetical protein -
ACU15_RS11660 2687284..2688135 - 852 WP_047339759.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
ACU15_RS11665 2688132..2688737 - 606 WP_024710981.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
ACU15_RS21880 2688981..2689766 - 786 WP_053056035.1 helix-turn-helix domain-containing protein -
ACU15_RS23665 2690092..2690268 + 177 WP_014503024.1 hypothetical protein -
ACU15_RS11675 2690575..2691660 + 1086 WP_048485514.1 sensor domain-containing diguanylate cyclase -
ACU15_RS11680 2691703..2692212 - 510 WP_014503022.1 chemotaxis protein CheW -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2669242..2697022 27780
flank IS/Tn - - 2682324..2683286 962


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(34-262)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(8-55)


Sequences

Toxin        


Download         Length: 284 a.a.        Molecular weight: 31056.91 Da        Isoelectric Point: 7.0657

>T55259 WP_047339759.1 NZ_CP011957:c2688135-2687284 [Xanthomonas oryzae pv. oryzicola]
MSNVAASVRARLRGVAKAQGVDFNQVLVRFALERILYRLSQSEHADRFLLKGALLFTLWYDMPHRATRDADLLGFGASDL
ESVAQTFRDIASVAVDDGIVFDPASVVAEEIRKDAGYAGARILIGGELAKARCRTQIDVGFGDAVTPAPVHSVYPVLLED
LPAPRLRTYPVYTVIAEKLHAIALLGMTNSRMKDYLDLSVLLERESLDIDLLAQAVKATFERRGMAVPAALPIGMTDEFA
HDTSRQALWQAFLKKNELAPEPLAAIVVRLRAALEPALHRAAR

Download         Length: 852 bp

>T55259 NZ_CP011957:c2688135-2687284 [Xanthomonas oryzae pv. oryzicola]
ATGAGCAACGTCGCCGCTTCCGTGCGCGCCCGCTTGCGGGGCGTCGCCAAGGCGCAGGGCGTGGATTTCAATCAGGTGCT
GGTGCGCTTCGCGCTGGAGCGCATCCTTTACCGCCTGAGCCAGTCCGAGCACGCGGATCGTTTCCTGCTCAAGGGCGCGC
TGCTGTTCACGCTCTGGTATGACATGCCGCACCGGGCCACGCGCGACGCCGACCTGCTGGGCTTCGGCGCGAGCGATCTG
GAGTCCGTGGCCCAGACCTTCCGCGACATCGCCAGCGTCGCCGTGGACGACGGCATCGTGTTCGACCCGGCCTCGGTCGT
CGCAGAAGAAATTCGCAAGGACGCCGGATACGCCGGGGCGCGCATCCTCATCGGCGGCGAGCTGGCCAAGGCGCGGTGCA
GGACGCAGATCGACGTTGGCTTCGGCGATGCGGTCACACCGGCTCCGGTGCACTCGGTCTATCCGGTGTTGCTGGAAGAT
CTGCCTGCGCCTCGCCTGCGCACCTATCCCGTCTACACCGTCATCGCGGAAAAGCTCCACGCCATCGCGCTTCTGGGTAT
GACCAACAGTCGGATGAAGGATTACCTCGACCTGTCGGTGCTGCTGGAACGCGAATCCCTGGACATCGATCTGCTGGCGC
AAGCGGTGAAGGCCACTTTCGAGCGACGCGGCATGGCCGTGCCCGCTGCTCTGCCGATCGGCATGACCGACGAGTTCGCG
CACGACACGTCTCGGCAGGCGCTGTGGCAGGCATTCCTCAAGAAGAACGAACTCGCCCCCGAACCCCTGGCTGCCATCGT
GGTTCGACTGCGGGCGGCCTTGGAACCAGCGTTGCACCGGGCTGCTCGATGA

Antitoxin


Download         Length: 202 a.a.        Molecular weight: 22257.92 Da        Isoelectric Point: 9.9253

>AT55259 WP_024710981.1 NZ_CP011957:c2688737-2688132 [Xanthomonas oryzae pv. oryzicola]
MLSDTHTQRVLDLASQKGLLRASDLDAINAPRVVLTRLTAAGVLERVGRGLYRLPDAQGSEFESLAAIATKVPQAVFCLL
TALQFHELTTQLPRQIWIAMPRGSHAPRIGYPPVKMVQMTGDVYAAGIEEHLRDGVRLRVYGAAKTVVDCFKHRNKIGLD
VALEALKDVRAKRKATADDLWRFATVCRVANVMRPYLEAVE

Download         Length: 606 bp

>AT55259 NZ_CP011957:c2688737-2688132 [Xanthomonas oryzae pv. oryzicola]
ATGCTTTCCGACACCCACACCCAGCGCGTCCTCGATCTGGCCAGCCAGAAAGGACTGCTGCGCGCCAGCGATCTGGACGC
CATCAATGCGCCCCGGGTCGTTCTCACGCGCCTGACCGCTGCTGGCGTTCTGGAAAGGGTCGGACGCGGGCTGTACCGCC
TGCCGGACGCGCAGGGATCGGAATTCGAGAGTCTCGCGGCCATCGCCACCAAGGTGCCACAAGCCGTGTTCTGCCTGCTG
ACTGCGCTGCAGTTCCACGAACTGACCACGCAACTGCCGCGCCAGATCTGGATCGCCATGCCGCGCGGCAGTCACGCGCC
CCGGATCGGCTATCCGCCGGTCAAGATGGTTCAGATGACCGGCGACGTCTACGCTGCAGGCATCGAGGAGCACCTGCGCG
ACGGCGTGAGGCTGCGCGTGTACGGTGCGGCCAAGACGGTCGTGGACTGCTTCAAGCACCGCAACAAGATCGGCCTGGAC
GTGGCGCTGGAGGCGCTGAAGGACGTGCGCGCCAAACGCAAGGCCACTGCGGACGACCTGTGGCGCTTTGCTACGGTCTG
CCGCGTGGCCAACGTGATGCGCCCCTATCTGGAGGCGGTCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A5C2EYQ5

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V250

References