Detailed information of TA system TA055146

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): bsrE-as-bsrE/-
• Location: 2979262..2979577
• Replicon: chromosome
• Accession: NZ_CP011882
• Organism: Bacillus subtilis strain TO-A JPC

Toxin (Protein)

• Gene name: bsrE
• Uniprot ID: -
• Locus tag: ABU16_RS22470
• Protein ID: WP_120322743.1
• Coordinates: 2979262..2979423 (+)
• Length: 54 a.a.

Antitoxin (RNA)

Gene name	as-bsrE
Locus tag	-
Coordinates	2979404..2979577 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ABU16_RS15075	2974490..2974825	+	336	WP_009967409.1	hypothetical protein	-
ABU16_RS15080	2974872..2978477	-	3606	WP_004399367.1	membrane protein	-
ABU16_RS15085	2978710..2979042	-	333	WP_026009814.1	hypothetical protein	-
ABU16_RS22470	2979262..2979423	+	162	WP_120322743.1	putative holin-like toxin	Toxin
-	2979404..2979577	-	174	-	-	Antitoxin
ABU16_RS15090	2979692..2980534	-	843	WP_003231327.1	hypothetical protein	-
ABU16_RS15095	2980734..2981192	-	459	WP_003231326.1	type II toxin-antitoxin system antitoxin YobK	-
ABU16_RS15100	2981202..2983004	-	1803	WP_004399481.1	type II toxin-antitoxin system toxin ribonuclease YobL	-
ABU16_RS15105	2983106..2983663	-	558	WP_004399321.1	SMI1/KNR4 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2965316..2990542	25226

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (24-47)

Sequences

Toxin

Protein

• Length: 54 a.a.
• Molecular weight: 5780.74 Da
• Isoelectric Point: 4.6641

>T55146 WP_120322743.1 NZ_CP011882:2979262-2979423 [Bacillus subtilis]
ISCTVSFAHSRESCSSPNERGDAMSTFQALMLMLAIGSFIIALLTYIEKIDLP

Nucleotide

• Length: 162 bp

>T55146 NZ_CP011882:2979262-2979423 [Bacillus subtilis]
ATTTCCTGTACAGTAAGTTTTGCTCACTCGAGGGAGTCTTGCTCATCCCCTAATGAAAGGGGTGATGCTATGTCAACATT
CCAGGCATTAATGCTAATGCTTGCAATCGGGTCGTTTATAATCGCCCTATTGACGTATATAGAAAAAATAGACCTCCCTT
GA

Antitoxin

Nucleotide

• Length: 174 bp

>AT55146 NZ_CP011882:c2979577-2979404 [Bacillus subtilis]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Structures

Antitoxin