Detailed information of TA system TA055082

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yefM-yoeB (relBE)/YoeB-YefM
• Location: 1468945..1469460
• Replicon: chromosome
• Accession: NZ_CP011835
• Organism: Azotobacter chroococcum strain B3

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: -
• Locus tag: ACG10_RS06845
• Protein ID: WP_089167646.1
• Coordinates: 1469206..1469460 (+)
• Length: 85 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: A0A0C4WNE7
• Locus tag: ACG10_RS06840
• Protein ID: WP_039805099.1
• Coordinates: 1468945..1469202 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ACG10_RS06830	1467053..1467466	+	414	WP_198319026.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACG10_RS06835	1467519..1468715	+	1197	WP_089169807.1	MFS transporter	-
ACG10_RS06840	1468945..1469202	+	258	WP_039805099.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
ACG10_RS06845	1469206..1469460	+	255	WP_089167646.1	Txe/YoeB family addiction module toxin	Toxin
ACG10_RS06850	1469454..1469831	-	378	WP_089167647.1	hypothetical protein	-
ACG10_RS06855	1469979..1470707	+	729	WP_089167648.1	SIMPL domain-containing protein	-
ACG10_RS06860	1470744..1471976	-	1233	WP_089167649.1	MFS transporter	-
ACG10_RS06865	1472489..1473505	-	1017	WP_039805088.1	AraC family transcriptional regulator	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-74)

Sequences

Toxin

Protein

• Length: 85 a.a.
• Molecular weight: 9962.37 Da
• Isoelectric Point: 7.2752

>T55082 WP_089167646.1 NZ_CP011835:1469206-1469460 [Azotobacter chroococcum]
MNILFTPEAWDDYLWFQQNDKAGLKRINLLIQDAQRDPFGGLGKPEPLKHNLSGFWSRRIGEEHRLVYRVDGDALQIVMC
RYHY

Nucleotide

• Length: 255 bp

>T55082 NZ_CP011835:1469206-1469460 [Azotobacter chroococcum]
TTGAACATTCTCTTCACGCCCGAGGCCTGGGACGACTACCTGTGGTTCCAGCAAAACGACAAGGCCGGGCTCAAGCGGAT
CAACCTGCTGATCCAGGATGCGCAACGCGATCCGTTCGGCGGTCTTGGCAAGCCGGAGCCCTTGAAGCACAACCTCAGCG
GTTTCTGGTCGCGCCGCATCGGCGAGGAACATCGGCTGGTCTACAGGGTGGACGGAGATGCTCTGCAGATCGTGATGTGC
CGTTATCACTACTGA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9570.84 Da
• Isoelectric Point: 5.8234

>AT55082 WP_039805099.1 NZ_CP011835:1468945-1469202 [Azotobacter chroococcum]
MQTINYTTARQHLAETMDRVNNDRTPILVTRQKGEPVVMISLADYNALEETAYLLRSPANAERLIRSIASLRAGKAEPRS
LVDED

Nucleotide

• Length: 258 bp

>AT55082 NZ_CP011835:1468945-1469202 [Azotobacter chroococcum]
ATGCAGACCATCAACTACACCACGGCACGCCAGCACCTGGCGGAAACCATGGATCGGGTGAACAACGACCGCACGCCCAT
CCTGGTCACCCGGCAGAAGGGCGAGCCGGTGGTGATGATTTCCCTGGCCGACTACAACGCTCTCGAGGAGACGGCCTATC
TGCTGCGCTCGCCGGCCAATGCGGAGCGTCTGATCCGCTCGATCGCCAGCCTGCGCGCCGGCAAGGCGGAGCCGCGGTCG
CTCGTCGACGAAGACTGA

Structures

Antitoxin

• AlphaFold DB: A0A0C4WNE7