Detailed information of TA system TA055058

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yefM-yoeB (relBE)/YoeB-RelB
• Location: 711402..711919
• Replicon: chromosome
• Accession: NZ_CP011805
• Organism: Pelagerythrobacter marensis strain KCTC 22370

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: A0A0G3X6F4
• Locus tag: AM2010_RS03435
• Protein ID: WP_047805886.1
• Coordinates: 711402..711668 (-)
• Length: 89 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: AM2010_RS03440
• Protein ID: WP_047805887.1
• Coordinates: 711665..711919 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AM2010_RS03410	707862..708326	+	465	WP_047805881.1	Lrp/AsnC family transcriptional regulator	-
AM2010_RS03415	708418..708885	+	468	WP_150115225.1	hypothetical protein	-
AM2010_RS03420	709021..710382	-	1362	WP_047805883.1	acetyl-CoA carboxylase biotin carboxylase subunit	-
AM2010_RS03425	710391..710846	-	456	WP_201784039.1	acetyl-CoA carboxylase biotin carboxyl carrier protein	-
AM2010_RS03430	710964..711398	-	435	WP_047805885.1	3-dehydroquinate dehydratase	-
AM2010_RS03435	711402..711668	-	267	WP_047805886.1	Txe/YoeB family addiction module toxin	Toxin
AM2010_RS03440	711665..711919	-	255	WP_047805887.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
AM2010_RS03445	711979..712392	-	414	WP_047807659.1	holin family protein	-
AM2010_RS03450	712465..713376	-	912	WP_047807660.1	CoA ester lyase	-
AM2010_RS03455	713547..714926	+	1380	WP_047805888.1	amidohydrolase family protein	-
AM2010_RS03460	714950..715921	+	972	WP_160325568.1	polysaccharide deacetylase family protein	-
AM2010_RS03470	716333..716653	+	321	WP_047805889.1	preprotein translocase subunit YajC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (5-88)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (3-71)

Sequences

Toxin

Protein

• Length: 89 a.a.
• Molecular weight: 10501.12 Da
• Isoelectric Point: 10.3159

>T55058 WP_047805886.1 NZ_CP011805:c711668-711402 [Pelagerythrobacter marensis]
VKIVFSSHAWEDYRYWCANDRKTLLRLNGLIEECRRNPFKGLGKPEPLRGELAGLWSRRINHRDRLVYRIAGKHPDQRLE
IVQCKGHY

Nucleotide

• Length: 267 bp

>T55058 NZ_CP011805:c711668-711402 [Pelagerythrobacter marensis]
GTGAAGATCGTCTTCTCCTCCCACGCCTGGGAAGATTACCGGTACTGGTGCGCGAATGATCGAAAAACACTGCTCCGCCT
GAACGGCCTGATCGAGGAATGCCGAAGAAATCCCTTCAAGGGACTGGGCAAGCCCGAGCCGCTTCGGGGCGAGCTTGCCG
GCCTCTGGTCCCGGCGGATTAACCACCGGGATCGTCTCGTCTACCGCATCGCCGGGAAGCATCCCGATCAAAGGCTGGAA
ATCGTTCAATGCAAAGGGCACTACTGA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9513.68 Da
• Isoelectric Point: 5.1363

>AT55058 WP_047805887.1 NZ_CP011805:c711919-711665 [Pelagerythrobacter marensis]
VDVMTYSDARKNLKSVMDKVVDHRSEVVVTRRNGEAVVMVSLSEWNSIVETEHLMASPKNARRLRESIAELDQDEGGEHD
LVHP

Nucleotide

• Length: 255 bp

>AT55058 NZ_CP011805:c711919-711665 [Pelagerythrobacter marensis]
GTGGATGTGATGACCTACAGCGATGCGCGCAAAAACCTGAAGAGCGTGATGGACAAGGTGGTGGACCACCGTTCCGAAGT
GGTCGTCACCCGCCGCAATGGAGAGGCTGTGGTGATGGTCTCGCTGTCCGAATGGAATTCTATTGTCGAGACCGAGCATC
TAATGGCGAGTCCGAAGAATGCCCGGCGGCTGCGCGAAAGCATTGCCGAACTCGATCAGGATGAAGGTGGCGAGCACGAT
CTGGTCCATCCGTGA

Structures

Toxin

• AlphaFold DB: A0A0G3X6F4