Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2251835..2252051 Replicon chromosome
Accession NZ_CP011685
Organism Staphylococcus aureus strain ZJ5499

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag AB179_RS11455 Protein ID WP_001802298.1
Coordinates 2251947..2252051 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2251835..2251890 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AB179_RS11435 2248041..2248706 - 666 WP_001024095.1 SDR family oxidoreductase -
AB179_RS11440 2248858..2249178 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
AB179_RS11445 2249180..2250157 + 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
AB179_RS11450 2250423..2251514 + 1092 WP_063653192.1 hypothetical protein -
- 2251835..2251890 + 56 - - Antitoxin
AB179_RS11455 2251947..2252051 - 105 WP_001802298.1 hypothetical protein Toxin
AB179_RS15345 2252568..2252738 + 171 WP_001792292.1 transposase -
AB179_RS14970 2252731..2252889 + 159 WP_001792784.1 hypothetical protein -
AB179_RS11460 2253547..2254404 - 858 WP_000370925.1 Cof-type HAD-IIB family hydrolase -
AB179_RS11465 2254472..2255254 - 783 WP_000908182.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin YafO

(27-130)


Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T54838 WP_001802298.1 NZ_CP011685:c2252051-2251947 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T54838 NZ_CP011685:c2252051-2251947 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT54838 NZ_CP011685:2251835-2251890 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References