Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1909753..1909933 Replicon chromosome
Accession NZ_CP011685
Organism Staphylococcus aureus strain ZJ5499

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag AB179_RS15225 Protein ID WP_001801861.1
Coordinates 1909753..1909848 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1909876..1909933 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AB179_RS09355 1904916..1905566 + 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -
AB179_RS09360 1905647..1906642 + 996 WP_000070642.1 DUF4352 domain-containing protein -
AB179_RS09365 1906717..1907343 + 627 WP_000669024.1 hypothetical protein -
AB179_RS09370 1907384..1907725 + 342 WP_000627540.1 DUF3969 family protein -
AB179_RS09375 1907826..1908398 + 573 WP_000414216.1 hypothetical protein -
AB179_RS14870 1908596..1909608 - 1013 Protein_1806 IS3 family transposase -
AB179_RS15225 1909753..1909848 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1909876..1909933 - 58 - - Antitoxin
AB179_RS09395 1909971..1910072 + 102 WP_001792025.1 hypothetical protein -
AB179_RS15230 1910050..1910211 - 162 Protein_1809 transposase -
AB179_RS09400 1910202..1910696 - 495 Protein_1810 transposase -
AB179_RS09405 1911148..1912377 - 1230 WP_000072627.1 restriction endonuclease subunit S -
AB179_RS09410 1912370..1913926 - 1557 WP_000028669.1 type I restriction-modification system subunit M -
AB179_RS09415 1914090..1914224 - 135 WP_001791797.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T54829 WP_001801861.1 NZ_CP011685:1909753-1909848 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T54829 NZ_CP011685:1909753-1909848 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT54829 NZ_CP011685:c1909933-1909876 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References