Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 4061206..4061860 Replicon chromosome
Accession NZ_CP011566
Organism Pseudomonas sp. DR 5-09

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag PDR5_RS18205 Protein ID WP_064597755.1
Coordinates 4061206..4061556 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag PDR5_RS18210 Protein ID WP_064597757.1
Coordinates 4061546..4061860 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PDR5_RS18190 4057298..4058830 + 1533 WP_011334963.1 NADH-quinone oxidoreductase subunit M -
PDR5_RS18195 4058838..4060301 + 1464 WP_064597748.1 NADH-quinone oxidoreductase subunit NuoN -
PDR5_RS18200 4060360..4060833 - 474 WP_064597750.1 GNAT family N-acetyltransferase -
PDR5_RS18205 4061206..4061556 + 351 WP_064597755.1 hypothetical protein Toxin
PDR5_RS18210 4061546..4061860 + 315 WP_064597757.1 transcriptional regulator Antitoxin
PDR5_RS18215 4062350..4063228 + 879 WP_064597759.1 alpha/beta fold hydrolase -
PDR5_RS18220 4063273..4065015 - 1743 WP_007951484.1 ABC transporter substrate-binding protein -
PDR5_RS18225 4065063..4065335 - 273 WP_039767461.1 DUF2160 domain-containing protein -
PDR5_RS18230 4065346..4066161 - 816 WP_064597762.1 carbohydrate ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-100)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13828.69 Da        Isoelectric Point: 7.9791

>T54532 WP_064597755.1 NZ_CP011566:4061206-4061556 [Pseudomonas sp. DR 5-09]
MDALFIELPAFQKHRNDYLDDDLFRSFQLELLKNPEAGDLIEGTGGLRKIRFCDQRRGKGKRSGLRVIYYWWPGFDQFWL
FTVYSKNEQDDLLPSQKRVFKQALDTEINTRAKYET

Download         Length: 351 bp

>T54532 NZ_CP011566:4061206-4061556 [Pseudomonas sp. DR 5-09]
ATGGATGCTCTTTTTATCGAATTACCCGCGTTCCAGAAGCACCGGAACGATTACCTGGATGATGATCTATTCCGCAGCTT
TCAGTTGGAGTTGCTGAAAAATCCCGAAGCGGGCGATCTCATCGAAGGCACGGGTGGGCTGCGCAAAATTCGCTTCTGCG
ACCAACGACGCGGAAAAGGCAAGCGCAGCGGATTACGAGTGATTTATTACTGGTGGCCTGGTTTCGACCAATTCTGGCTG
TTCACCGTGTACAGCAAAAACGAGCAAGACGATCTGTTGCCTTCCCAGAAAAGAGTCTTCAAACAGGCATTGGATACAGA
AATCAACACGAGAGCCAAATATGAAACGTGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11931.82 Da        Isoelectric Point: 9.9898

>AT54532 WP_064597757.1 NZ_CP011566:4061546-4061860 [Pseudomonas sp. DR 5-09]
MKRDIFSELMEGMEALADERQGKVTLRTHKVQLPKLLPITAEEVVAIRQQLNLSRSVFAMYLRTNTRTLENWEQGRATPN
AQATTLIRLVERFPQTIDHLAALT

Download         Length: 315 bp

>AT54532 NZ_CP011566:4061546-4061860 [Pseudomonas sp. DR 5-09]
ATGAAACGTGACATTTTTTCCGAACTGATGGAGGGCATGGAGGCTTTGGCTGACGAGCGCCAGGGCAAGGTCACCCTTCG
AACCCACAAAGTCCAATTACCAAAGCTGTTGCCGATAACCGCGGAGGAAGTGGTCGCGATCCGCCAACAACTCAACCTCT
CCAGGTCAGTGTTCGCCATGTATCTGCGAACCAACACACGAACTCTCGAAAACTGGGAACAAGGTCGAGCAACGCCAAAT
GCCCAAGCGACGACACTCATTCGACTGGTCGAGCGTTTTCCACAAACGATCGACCATCTTGCGGCTCTGACCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References