Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 914435..914927 Replicon chromosome
Accession NZ_CP011545
Organism Corynebacterium testudinoris strain DSM 44614

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag CTEST_RS04505 Protein ID WP_047252729.1
Coordinates 914435..914689 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag CTEST_RS04510 Protein ID WP_047252730.1
Coordinates 914670..914927 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CTEST_RS13720 910130..910909 + 780 WP_162488752.1 CPBP family intramembrane metalloprotease -
CTEST_RS13025 911243..911842 + 600 WP_144413219.1 hypothetical protein -
CTEST_RS13030 912018..912590 + 573 WP_052844299.1 hypothetical protein -
CTEST_RS04495 912823..913950 + 1128 WP_047252727.1 low temperature requirement protein A -
CTEST_RS04500 913988..914428 + 441 WP_047252728.1 YtoQ family protein -
CTEST_RS04505 914435..914689 - 255 WP_047252729.1 Txe/YoeB family addiction module toxin Toxin
CTEST_RS04510 914670..914927 - 258 WP_047252730.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
CTEST_RS04515 914937..915629 - 693 WP_047252731.1 type 1 glutamine amidotransferase domain-containing protein -
CTEST_RS04520 915640..916206 - 567 WP_047252732.1 TetR/AcrR family transcriptional regulator -
CTEST_RS04525 916309..917586 - 1278 WP_047252733.1 NADH:flavin oxidoreductase/NADH oxidase family protein -
CTEST_RS04530 917619..918674 - 1056 WP_047252734.1 hypothetical protein -
CTEST_RS04535 918737..919222 + 486 WP_047252735.1 DinB family protein -
CTEST_RS04540 919207..919587 - 381 WP_144413220.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 908698..910110 1412


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10179.62 Da        Isoelectric Point: 8.8754

>T54528 WP_047252729.1 NZ_CP011545:c914689-914435 [Corynebacterium testudinoris]
MPPVWDEHAWDDYLWWQTQDRKVLKRINLLVKDIVRNGNEGIGKPEPLKHDFAGYWSRRVTDEHRLVYKLTATELRIAAC
RYHY

Download         Length: 255 bp

>T54528 NZ_CP011545:c914689-914435 [Corynebacterium testudinoris]
ATGCCGCCTGTCTGGGATGAGCATGCGTGGGACGACTATCTCTGGTGGCAAACGCAAGACCGAAAAGTACTGAAAAGAAT
CAACCTGCTAGTGAAAGACATTGTCCGAAACGGCAATGAGGGGATTGGCAAACCGGAGCCGCTGAAGCACGACTTCGCCG
GCTACTGGTCTCGCCGCGTCACCGACGAGCACCGGCTCGTCTATAAACTCACCGCAACAGAGCTTCGCATTGCCGCCTGC
CGCTATCACTACTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9453.60 Da        Isoelectric Point: 4.7914

>AT54528 WP_047252730.1 NZ_CP011545:c914927-914670 [Corynebacterium testudinoris]
MRTMSYTESRANYAQVLDDVTNDREAIVVTRAGHDPVVMVSLADYESLRETAYLLRSPANARRLLDAMERLEAGRGEPHD
AACLG

Download         Length: 258 bp

>AT54528 NZ_CP011545:c914927-914670 [Corynebacterium testudinoris]
ATGAGAACTATGAGCTACACCGAGTCACGTGCCAACTACGCACAGGTTCTGGACGATGTGACCAATGATCGCGAAGCAAT
CGTCGTTACTCGAGCCGGACACGACCCTGTCGTCATGGTCTCGCTCGCCGATTACGAATCCCTTCGAGAAACTGCTTACC
TGCTCCGCTCCCCCGCTAACGCGCGGCGTCTTCTCGACGCCATGGAACGCCTTGAAGCCGGCCGCGGCGAACCACATGAT
GCCGCCTGTCTGGGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References