54488

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-sprA1AS/-
Location 2140919..2141116 Replicon chromosome
Accession NZ_CP011528
Organism Staphylococcus aureus strain RKI4

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag AA961_RS15175 Protein ID WP_001802298.1
Coordinates 2141012..2141116 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2140919..2140957 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AA961_RS10820 2137094..2137759 - 666 WP_001024095.1 SDR family oxidoreductase -
AA961_RS10825 2137911..2138231 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
AA961_RS10830 2138233..2139213 + 981 WP_000019743.1 CDF family zinc efflux transporter CzrB -
AA961_RS10835 2139479..2140570 + 1092 WP_000495681.1 hypothetical protein -
- 2140919..2140957 + 39 - - Antitoxin
AA961_RS15175 2141012..2141116 - 105 WP_001802298.1 hypothetical protein Toxin
AA961_RS15780 2141633..2141803 + 171 WP_001792292.1 transposase -
AA961_RS15185 2141796..2141954 + 159 WP_001792784.1 hypothetical protein -
AA961_RS10845 2142612..2143469 - 858 WP_047928586.1 Cof-type HAD-IIB family hydrolase -
AA961_RS10850 2143537..2144319 - 783 WP_000908180.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T54488 WP_001802298.1 NZ_CP011528:c2141116-2141012 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T54488 NZ_CP011528:c2141116-2141012 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 39 bp

>AT54488 NZ_CP011528:2140919-2140957 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References