Detailed information of TA system TA054478

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1798831..1799011
• Replicon: chromosome
• Accession: NZ_CP011528
• Organism: Staphylococcus aureus strain RKI4

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: AA961_RS15715
• Protein ID: WP_144412207.1
• Coordinates: 1798831..1798926 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1798954..1799011 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AA961_RS08820	1794887..1795513	+	627	WP_000669028.1	hypothetical protein	-
AA961_RS08825	1795540..1796283	+	744	WP_175393121.1	exotoxin	-
AA961_RS08830	1796310..1797062	+	753	WP_000764922.1	staphylococcal enterotoxin type 27	-
AA961_RS08835	1797194..1797750	-	557	Protein_1699	ImmA/IrrE family metallo-endopeptidase	-
AA961_RS08840	1797934..1798380	-	447	WP_000747805.1	DUF1433 domain-containing protein	-
AA961_RS14875	1798462..1798687	-	226	Protein_1701	hypothetical protein	-
AA961_RS15715	1798831..1798926	+	96	WP_144412207.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	1798954..1799011	-	58	-	-	Antitoxin
AA961_RS08845	1799577..1801273	-	1697	Protein_1703	hypothetical protein	-
AA961_RS08850	1801251..1802101	-	851	Protein_1704	DNA adenine methylase	-
AA961_RS08855	1802140..1803405	-	1266	WP_000072555.1	restriction endonuclease subunit S	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	selk	1792329..1820290	27961

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3586.32 Da
• Isoelectric Point: 9.7764

>T54478 WP_144412207.1 NZ_CP011528:1798831-1798926 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAVAYYTYWLSRRNTK

Nucleotide

• Length: 96 bp

>T54478 NZ_CP011528:1798831-1798926 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCTGTTGCGTATTATACTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT54478 NZ_CP011528:c1799011-1798954 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin