54472

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2146505..2146768 Replicon chromosome
Accession NZ_CP011526
Organism Staphylococcus aureus strain DSM 20231

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag AA076_RS15430 Protein ID WP_001802298.1
Coordinates 2146664..2146768 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2146505..2146669 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AA076_RS10860 2142688..2143353 - 666 WP_001024094.1 SDR family oxidoreductase -
AA076_RS10865 2143505..2143825 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
AA076_RS10870 2143827..2144807 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
AA076_RS10875 2145073..2146164 + 1092 WP_000495671.1 lytic regulatory protein -
- 2146505..2146669 + 165 - - Antitoxin
AA076_RS15430 2146664..2146768 - 105 WP_001802298.1 hypothetical protein Toxin
AA076_RS15965 2146929..2147412 - 484 Protein_2047 recombinase family protein -
AA076_RS10890 2147455..2148591 - 1137 WP_000115562.1 SAP domain-containing protein -
AA076_RS15435 2148880..2148972 + 93 WP_001790138.1 hypothetical protein -
AA076_RS10900 2149677..2150534 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
AA076_RS10905 2150602..2151384 - 783 WP_000908177.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T54472 WP_001802298.1 NZ_CP011526:c2146768-2146664 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T54472 NZ_CP011526:c2146768-2146664 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT54472 NZ_CP011526:2146505-2146669 [Staphylococcus aureus]
GTAGCAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References