Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 276320..276542 Replicon chromosome
Accession NZ_CP011495
Organism Escherichia coli strain NCM3722 isolate K-12

Toxin (Protein)


Gene name ldrD Uniprot ID S1E8T8
Locus tag AA953_RS01375 Protein ID WP_000141634.1
Coordinates 276320..276427 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 276476..276542 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AA953_RS01350 271573..272325 - 753 Protein_256 cellulose biosynthesis protein BcsQ -
AA953_RS01355 272337..272525 - 189 WP_001063318.1 YhjR family protein -
AA953_RS01360 272798..274369 + 1572 WP_001204931.1 cellulose biosynthesis protein BcsE -
AA953_RS01365 274366..274557 + 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
AA953_RS01370 274554..276233 + 1680 WP_000191622.1 cellulose biosynthesis protein BcsG -
AA953_RS01375 276320..276427 - 108 WP_000141634.1 type I toxin-antitoxin system toxic polypeptide LdrD Toxin
- 276476..276542 + 67 - - Antitoxin
AA953_RS01385 276903..278174 + 1272 WP_001295225.1 transporter -
AA953_RS01390 278204..279208 - 1005 WP_000107012.1 dipeptide ABC transporter ATP-binding subunit DppF -
AA953_RS01395 279205..280188 - 984 WP_001196486.1 dipeptide ABC transporter ATP-binding protein -
AA953_RS01400 280199..281101 - 903 WP_000084677.1 dipeptide ABC transporter permease DppC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3916.72 Da        Isoelectric Point: 9.0157

>T54300 WP_000141634.1 NZ_CP011495:c276427-276320 [Escherichia coli]
MTFAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T54300 NZ_CP011495:c276427-276320 [Escherichia coli]
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 67 bp

>AT54300 NZ_CP011495:276476-276542 [Escherichia coli]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 5LBJ

Antitoxin

Download structure file

References