Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 3578599..3579202 Replicon chromosome
Accession NZ_CP011409
Organism Herbaspirillum hiltneri N3

Toxin (Protein)


Gene name graT Uniprot ID -
Locus tag F506_RS16350 Protein ID WP_053199151.1
Coordinates 3578924..3579202 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag F506_RS16345 Protein ID WP_053199149.1
Coordinates 3578599..3578910 (-) Length 104 a.a.

Genomic Context

F506_RS16340F506_RS22740F506_RS16335F506_RS16345F506_RS16350F506_RS16355F506_RS16360
Location: 3577085..3578005 (921 bp)
Type: Others
Protein ID: WP_053199147.1
Location: 3578272..3578568 (297 bp)
Type: Others
Protein ID: WP_083457962.1
Location: 3574638..3576950 (2313 bp)
Type: Others
Protein ID: WP_053199145.1
Location: 3578599..3578910 (312 bp)
Type: Antitoxin
Protein ID: WP_053199149.1
Location: 3578924..3579202 (279 bp)
Type: Toxin
Protein ID: WP_053199151.1
Location: 3579455..3581146 (1692 bp)
Type: Others
Protein ID: WP_053199153.1
Location: 3581450..3584041 (2592 bp)
Type: Others
Protein ID: WP_053199155.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
F506_RS163353574638..3576950-2313WP_053199145.15-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase-
F506_RS163403577085..3578005+921WP_053199147.1LysR family transcriptional regulator-
F506_RS227403578272..3578568+297WP_083457962.1hypothetical protein-
F506_RS163453578599..3578910-312WP_053199149.1HigA family addiction module antidote proteinAntitoxin
F506_RS163503578924..3579202-279WP_053199151.1type II toxin-antitoxin system RelE/ParE family toxinToxin
F506_RS163553579455..3581146-1692WP_053199153.1sensor domain-containing diguanylate cyclase-
F506_RS163603581450..3584041-2592WP_053199155.1ATP-dependent chaperone ClpB-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(1-92)

Antitoxin

Toxin-antitoxin system, antidote protein, HigA

(6-99)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10610.02 Da        Isoelectric Point: 7.8607

>T54197 WP_053199151.1 NZ_CP011409:c3579202-3578924 [Herbaspirillum hiltneri N3]
MILSFQCKDTESFYQGQSVARFANFRNTAERKLQMLDSAVTLDFLRSPPGNRLEALIGNRAGQHSIRINDQFRICFVWTD
KGPTQVEIVDYH

Download         Length: 279 bp

>T54197 NZ_CP011409:c3579202-3578924 [Herbaspirillum hiltneri N3]
ATGATACTTAGCTTCCAATGCAAAGATACCGAGTCCTTTTACCAAGGGCAGAGCGTTGCGAGGTTTGCAAATTTCAGAAA
CACAGCTGAACGCAAACTGCAAATGCTTGACTCCGCAGTAACGTTGGACTTTCTCCGTTCTCCACCGGGAAATCGGTTGG
AGGCGCTCATCGGCAATCGTGCCGGGCAGCACAGTATCAGGATCAACGATCAATTCCGTATCTGTTTCGTGTGGACTGAT
AAGGGACCAACTCAAGTCGAGATCGTGGATTACCACTGA

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11505.35 Da        Isoelectric Point: 5.7203

>AT54197 WP_053199149.1 NZ_CP011409:c3578910-3578599 [Herbaspirillum hiltneri N3]
MTKLINRMRPVHPGEILKEDFLAPAELSANALAIALHVPATRIGEIINERRGITPDTALRLARFFGGDAQSWLNLQLAYD
LKITEMEVGERIEREIQPMAQAA

Download         Length: 312 bp

>AT54197 NZ_CP011409:c3578910-3578599 [Herbaspirillum hiltneri N3]
ATGACTAAATTAATTAATCGTATGCGCCCGGTTCATCCGGGCGAAATTCTTAAAGAAGACTTTCTTGCTCCTGCAGAGTT
GAGCGCCAATGCATTGGCTATTGCCTTGCACGTCCCTGCTACGCGTATTGGGGAAATCATCAATGAACGCCGAGGTATTA
CTCCGGACACCGCCTTGCGACTCGCGCGCTTCTTTGGCGGCGACGCCCAATCCTGGCTGAATCTGCAGCTCGCTTACGAT
CTCAAAATAACTGAGATGGAAGTGGGCGAACGGATCGAACGAGAAATTCAGCCTATGGCGCAGGCTGCATAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References