Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 3680209..3680431 Replicon chromosome
Accession NZ_CP011324
Organism Escherichia coli strain SQ2203

Toxin (Protein)


Gene name ldrD Uniprot ID S1E8T8
Locus tag CS35_RS18240 Protein ID WP_000141634.1
Coordinates 3680209..3680316 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 3680365..3680431 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CS35_RS18215 3675462..3676214 - 753 Protein_3493 cellulose biosynthesis protein BcsQ -
CS35_RS18220 3676226..3676414 - 189 WP_001063318.1 YhjR family protein -
CS35_RS18225 3676687..3678258 + 1572 WP_001204931.1 cellulose biosynthesis protein BcsE -
CS35_RS18230 3678255..3678446 + 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
CS35_RS18235 3678443..3680122 + 1680 WP_000191622.1 cellulose biosynthesis protein BcsG -
CS35_RS18240 3680209..3680316 - 108 WP_000141634.1 type I toxin-antitoxin system toxic polypeptide LdrD Toxin
- 3680365..3680431 + 67 - - Antitoxin
CS35_RS18250 3680792..3682063 + 1272 WP_001295225.1 transporter -
CS35_RS18255 3682093..3683097 - 1005 WP_000107012.1 dipeptide ABC transporter ATP-binding subunit DppF -
CS35_RS18260 3683094..3684077 - 984 WP_001196486.1 dipeptide ABC transporter ATP-binding protein -
CS35_RS18265 3684088..3684990 - 903 WP_000084677.1 dipeptide ABC transporter permease DppC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3916.72 Da        Isoelectric Point: 9.0157

>T53991 WP_000141634.1 NZ_CP011324:c3680316-3680209 [Escherichia coli]
MTFAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T53991 NZ_CP011324:c3680316-3680209 [Escherichia coli]
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 67 bp

>AT53991 NZ_CP011324:3680365-3680431 [Escherichia coli]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 5LBJ

Antitoxin

Download structure file

References