Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 3592661..3593355 Replicon chromosome
Accession NZ_CP011286
Organism Yersinia enterocolitica strain KNG22703

Toxin (Protein)


Gene name mqsR Uniprot ID A0A7U7FJ92
Locus tag XM56_RS16140 Protein ID WP_005166025.1
Coordinates 3593059..3593355 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID A0A7U7IQA2
Locus tag XM56_RS16135 Protein ID WP_005166024.1
Coordinates 3592661..3593059 (-) Length 133 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XM56_RS16110 3588061..3589305 - 1245 WP_005166619.1 sensor domain-containing diguanylate cyclase -
XM56_RS16115 3589388..3589783 - 396 WP_005166615.1 SgcJ/EcaC family oxidoreductase -
XM56_RS16120 3590155..3590991 - 837 Protein_3170 Fic family protein -
XM56_RS16125 3591009..3591209 + 201 WP_005166614.1 AlpA family transcriptional regulator -
XM56_RS16130 3591352..3592554 + 1203 WP_005176946.1 IS256 family transposase -
XM56_RS16135 3592661..3593059 - 399 WP_005166024.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
XM56_RS16140 3593059..3593355 - 297 WP_005166025.1 type II toxin-antitoxin system MqsR family toxin Toxin
XM56_RS16145 3593512..3593874 - 363 WP_005166026.1 helix-turn-helix domain-containing protein -
XM56_RS16150 3593940..3594200 - 261 WP_005166028.1 type II toxin-antitoxin system RelE/ParE family toxin -
XM56_RS16155 3595414..3595878 - 465 WP_032904770.1 helix-turn-helix domain-containing protein -
XM56_RS16160 3596118..3596612 + 495 WP_032904342.1 hypothetical protein -
XM56_RS16165 3596655..3597824 - 1170 WP_032904343.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(2-97)

Antitoxin

Cro/C1-type helix-turn-helix domain

(75-128)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11322.18 Da        Isoelectric Point: 7.7766

>T53771 WP_005166025.1 NZ_CP011286:c3593355-3593059 [Yersinia enterocolitica]
MEKRTPHTRLLKVKELVLKGNVKSTRTARDGAEELGLSFRDMCDVVCELTSADFYKSMTTHQDHTIWQDVYRPMLSCGRV
YLKITVIDDVLIVSFKEL

Download         Length: 297 bp

>T53771 NZ_CP011286:c3593355-3593059 [Yersinia enterocolitica]
ATGGAGAAACGGACTCCGCATACTCGTTTACTAAAAGTAAAAGAATTGGTATTGAAAGGGAATGTTAAATCGACTCGAAC
TGCCAGAGATGGCGCTGAAGAGCTGGGGCTGAGTTTTAGGGATATGTGTGATGTAGTTTGCGAACTGACTAGCGCCGATT
TTTATAAAAGTATGACGACACATCAAGATCATACGATTTGGCAGGATGTTTACCGCCCCATGCTTTCGTGCGGTAGAGTT
TATTTGAAAATCACGGTTATCGATGATGTTTTGATTGTCTCGTTTAAGGAGCTTTAA

Antitoxin


Download         Length: 133 a.a.        Molecular weight: 14716.19 Da        Isoelectric Point: 8.8165

>AT53771 WP_005166024.1 NZ_CP011286:c3593059-3592661 [Yersinia enterocolitica]
MMKCPVCGGAELIHEARDVPFTYKGRKFIVEGVIGQHCPACGETIMTEAESDTYAAKTMLLRKMVNTESIAPAYIVQVRK
KLGLNQREASEIFGGGVNAFSRYEKGKALPHRSTIKLLQVLDKYPELLNEIR

Download         Length: 399 bp

>AT53771 NZ_CP011286:c3593059-3592661 [Yersinia enterocolitica]
ATGATGAAATGCCCAGTTTGTGGTGGTGCAGAATTAATCCACGAAGCGCGTGACGTCCCCTTTACCTATAAAGGGCGTAA
GTTCATCGTCGAAGGCGTGATAGGACAACATTGCCCGGCATGCGGTGAAACAATCATGACTGAAGCTGAGTCCGATACCT
ATGCCGCAAAAACAATGCTTTTGCGAAAAATGGTTAATACAGAATCGATTGCACCCGCATATATTGTGCAGGTGCGAAAA
AAATTGGGTCTAAACCAGCGGGAAGCTAGTGAGATTTTTGGCGGTGGAGTGAATGCTTTTTCGCGTTACGAAAAGGGTAA
GGCGTTGCCACACCGTTCAACGATAAAATTGTTGCAAGTGCTTGATAAATATCCTGAGTTATTGAATGAAATCAGGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7U7FJ92

Antitoxin

Source ID Structure
AlphaFold DB A0A7U7IQA2

References