Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2251636..2251852 Replicon chromosome
Accession NZ_CP011147
Organism Staphylococcus aureus strain FCFHV36

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag FCFHV36_RS15735 Protein ID WP_001802298.1
Coordinates 2251748..2251852 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2251636..2251691 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FCFHV36_RS11420 2247842..2248507 - 666 WP_001024095.1 SDR family oxidoreductase -
FCFHV36_RS11425 2248659..2248979 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
FCFHV36_RS11430 2248981..2249958 + 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
FCFHV36_RS11435 2250224..2251315 + 1092 WP_000495669.1 hypothetical protein -
- 2251636..2251691 + 56 - - Antitoxin
FCFHV36_RS15735 2251748..2251852 - 105 WP_001802298.1 hypothetical protein Toxin
FCFHV36_RS15745 2252532..2252690 + 159 WP_001792784.1 hypothetical protein -
FCFHV36_RS11445 2253348..2254205 - 858 WP_000370923.1 Cof-type HAD-IIB family hydrolase -
FCFHV36_RS11450 2254273..2255055 - 783 WP_000908182.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T53573 WP_001802298.1 NZ_CP011147:c2251852-2251748 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T53573 NZ_CP011147:c2251852-2251748 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT53573 NZ_CP011147:2251636-2251691 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References