Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 15202..15743 Replicon plasmid unnamed3
Accession NZ_CP011123
Organism Acetobacter oryzifermentans strain SLV-7

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag WG31_RS14735 Protein ID WP_063355075.1
Coordinates 15202..15471 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag WG31_RS14740 Protein ID WP_063355076.1
Coordinates 15468..15743 (-) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
WG31_RS14720 10444..11034 - 591 WP_063355074.1 recombinase family protein -
WG31_RS14725 11251..13677 + 2427 WP_082823255.1 Hint domain-containing protein -
WG31_RS14730 13895..14974 - 1080 WP_063354378.1 IS5/IS1182 family transposase -
WG31_RS15685 15028..15189 - 162 WP_157884550.1 hypothetical protein -
WG31_RS14735 15202..15471 - 270 WP_063355075.1 Txe/YoeB family addiction module toxin Toxin
WG31_RS14740 15468..15743 - 276 WP_063355076.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
WG31_RS14745 15796..18888 - 3093 WP_063355081.1 Ti-type conjugative transfer relaxase TraA -
WG31_RS14750 18985..19344 + 360 WP_167348745.1 conjugal transfer protein TraD -
WG31_RS14755 19409..19675 + 267 WP_063355078.1 conjugal transfer protein TraD -
WG31_RS14760 19668..20171 + 504 WP_063355082.1 MucR family transcriptional regulator -
WG31_RS14765 20252..20659 - 408 WP_048848526.1 DUF2442 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..25290 25290
- flank IS/Tn - - 9661..10278 617


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-89)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-75)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10541.91 Da        Isoelectric Point: 8.0800

>T53480 WP_063355075.1 NZ_CP011123:c15471-15202 [Acetobacter oryzifermentans]
VKVFFHENGWEDYLSWFQSNTAVLEKINTLIDDVRRHPFQGLGKPEPLKGQLSGWWSRRITGEHRLVYRVQGRAGEDQLI
EVAQCRFHY

Download         Length: 270 bp

>T53480 NZ_CP011123:c15471-15202 [Acetobacter oryzifermentans]
GTGAAGGTCTTTTTTCATGAAAATGGCTGGGAGGATTATCTTTCCTGGTTTCAGTCAAACACTGCGGTTCTTGAGAAGAT
CAATACCCTGATCGACGATGTAAGGCGGCATCCATTTCAGGGGCTGGGCAAGCCGGAACCATTGAAGGGGCAGCTTTCCG
GGTGGTGGTCCCGACGGATTACGGGAGAACATCGTCTGGTCTACCGGGTTCAGGGGCGCGCGGGAGAGGATCAGCTGATT
GAGGTTGCCCAGTGCCGGTTTCATTACTGA

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10220.59 Da        Isoelectric Point: 7.2780

>AT53480 WP_063355076.1 NZ_CP011123:c15743-15468 [Acetobacter oryzifermentans]
MTCVSYTDLRQNLAHYLDEAVNSRAPIVVTRKTGKGSVVLMSEEEFSGWQETVHLLSSPRNAERLLRSIRDIEHGAATER
DLLKQQGKPLA

Download         Length: 276 bp

>AT53480 NZ_CP011123:c15743-15468 [Acetobacter oryzifermentans]
ATGACCTGTGTTTCCTATACCGACCTGCGCCAGAACCTGGCGCATTATCTGGATGAAGCCGTAAACAGCCGCGCGCCGAT
TGTCGTGACCCGCAAGACCGGGAAAGGCAGTGTCGTGCTGATGTCGGAAGAAGAATTCTCCGGCTGGCAGGAAACCGTGC
ATCTCCTGAGCAGCCCCCGTAACGCGGAGAGGCTGTTGCGGAGCATCCGAGACATTGAGCACGGGGCCGCGACCGAGCGT
GATCTTTTGAAGCAGCAGGGTAAACCGTTGGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References