Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 1709..2250 Replicon plasmid unnamed3
Accession NZ_CP011123
Organism Acetobacter oryzifermentans strain SLV-7

Toxin (Protein)


Gene name yoeB Uniprot ID A0A252ELZ7
Locus tag WG31_RS14645 Protein ID WP_039891754.1
Coordinates 1709..1978 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID F1YTL2
Locus tag WG31_RS14650 Protein ID WP_006116374.1
Coordinates 1975..2250 (-) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
WG31_RS15675 506..613 + 108 Protein_1 antitoxin -
WG31_RS14635 908..1303 - 396 WP_006116372.1 type II toxin-antitoxin system death-on-curing family toxin -
WG31_RS14640 1300..1527 - 228 WP_039891752.1 AbrB family transcriptional regulator -
WG31_RS14645 1709..1978 - 270 WP_039891754.1 Txe/YoeB family addiction module toxin Toxin
WG31_RS14650 1975..2250 - 276 WP_006116374.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
WG31_RS15680 3076..3249 + 174 WP_157884551.1 hypothetical protein -
WG31_RS14660 3598..3972 + 375 WP_139018868.1 hypothetical protein -
WG31_RS15370 3986..4318 + 333 WP_081461445.1 hypothetical protein -
WG31_RS14665 4374..4778 - 405 WP_063355066.1 DUF2442 domain-containing protein -
WG31_RS15730 4856..5089 - 234 WP_063355067.1 hypothetical protein -
WG31_RS14675 5091..5513 - 423 WP_039891761.1 type II toxin-antitoxin system VapC family toxin -
WG31_RS14680 5510..5755 - 246 WP_170315311.1 plasmid stabilization protein -
WG31_RS14690 6206..6448 - 243 WP_209439406.1 BrnA antitoxin family protein -
WG31_RS14695 6429..6737 - 309 WP_063355070.1 BrnT family toxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..25290 25290


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-89)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-75)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10660.00 Da        Isoelectric Point: 6.9785

>T53479 WP_039891754.1 NZ_CP011123:c1978-1709 [Acetobacter oryzifermentans]
VTVVFHEDGWEDYLSWFRSDHAVLEKINALIEDVRRHPFQGLGKPEPLKGQLSGWWSRRITGEHRLVYRVQGRVEEDQRI
EVAQCRFHY

Download         Length: 270 bp

>T53479 NZ_CP011123:c1978-1709 [Acetobacter oryzifermentans]
GTGACAGTCGTTTTTCATGAAGATGGCTGGGAGGATTATCTTTCGTGGTTCCGCTCAGACCATGCGGTTCTTGAGAAGAT
CAATGCCCTGATTGAGGATGTAAGGCGGCATCCGTTTCAGGGGCTGGGCAAGCCGGAACCGCTGAAAGGTCAGCTTTCCG
GGTGGTGGTCTCGTCGGATTACGGGAGAACATCGTCTGGTCTACCGGGTTCAGGGGCGTGTGGAGGAGGATCAGCGGATT
GAGGTCGCACAGTGTCGGTTTCATTACTGA

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10224.36 Da        Isoelectric Point: 4.8562

>AT53479 WP_006116374.1 NZ_CP011123:c2250-1975 [Acetobacter oryzifermentans]
MTCVSYTDLRQNLAHYLDEAVNSRAPIVVTRKTGKGSVVLMSEEEFSGWQETVHLLSSPRNAERLLRSIRDIEHGTATEH
DLLEPQGESSE

Download         Length: 276 bp

>AT53479 NZ_CP011123:c2250-1975 [Acetobacter oryzifermentans]
ATGACCTGTGTTTCCTATACCGACTTGCGCCAGAACCTGGCGCATTATCTGGACGAAGCCGTGAACAGCCGCGCGCCGAT
TGTCGTGACCCGCAAGACCGGGAAAGGCAGTGTCGTGCTGATGTCGGAAGAAGAATTCTCCGGCTGGCAGGAGACCGTGC
ATCTCCTGAGCAGCCCGCGCAACGCGGAGAGGCTGTTGCGGAGTATCCGAGACATTGAGCACGGGACCGCGACCGAGCAT
GATCTTCTGGAGCCGCAGGGTGAATCGTCAGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A252ELZ7

Antitoxin

Source ID Structure
AlphaFold DB A0A252ELY2

References