Detailed information of TA system TA053343

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2522625..2522950
• Replicon: chromosome
• Accession: NZ_CP011101
• Organism: Bacillus sp. LM 4-2

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: P54373
• Locus tag: bslm_RS12555
• Protein ID: WP_004398662.1
• Coordinates: 2522625..2522804 (+)
• Length: 60 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2522728..2522950 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
bslm_RS20855	2521851..2521988	-	138	WP_021480099.1	hypothetical protein	-
bslm_RS12550	2522030..2522479	-	450	WP_032722171.1	phage portal protein	-
bslm_RS12555	2522625..2522804	+	180	WP_004398662.1	type I toxin-antitoxin system toxin TxpA	Toxin
-	2522728..2522950	-	223	NuclAT_0	-	Antitoxin
-	2522728..2522950	-	223	NuclAT_0	-	Antitoxin
-	2522728..2522950	-	223	NuclAT_0	-	Antitoxin
-	2522728..2522950	-	223	NuclAT_0	-	Antitoxin
bslm_RS21365	2523184..2523273	+	90	WP_075058862.1	type I toxin-antitoxin system toxin BsrH	-
bslm_RS12560	2523527..2523970	-	444	WP_003229930.1	phage tail tube protein	-
bslm_RS12565	2523973..2525373	-	1401	WP_003229929.1	phage tail sheath family protein	-
bslm_RS12570	2525374..2525565	-	192	WP_010886574.1	hypothetical protein	-
bslm_RS12575	2525562..2525999	-	438	WP_003229927.1	hypothetical protein	-
bslm_RS12580	2526012..2526515	-	504	WP_003246050.1	HK97 gp10 family phage protein	-
bslm_RS12585	2526512..2526874	-	363	WP_003229925.1	YqbH/XkdH family protein	-
bslm_RS12590	2526871..2527266	-	396	WP_004398566.1	DUF3199 family protein	-
bslm_RS12595	2527270..2527581	-	312	WP_003229923.1	YqbF domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2489785..2546139	56354

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 60 a.a.
• Molecular weight: 6739.19 Da
• Isoelectric Point: 8.0370

>T53343 WP_004398662.1 NZ_CP011101:2522625-2522804 [Bacillus sp. LM 4-2]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG

Nucleotide

• Length: 180 bp

>T53343 NZ_CP011101:2522625-2522804 [Bacillus sp. LM 4-2]
ATGTCGACCTATGAATCTCTAATGGTCATGATCGGCTTTGCCAATTTAATAGGCGGGATTATGACATGGGTAATATCTCT
TTTAACATTATTATTCATGCTTAGAAAAAAAGACACTCATCCTATTTACATTACTGTAAAGGAAAAGTGTCTACACGAGG
ACCCTCCTATTAAAGGGTAG

Antitoxin

Nucleotide

• Length: 223 bp

>AT53343 NZ_CP011101:c2522950-2522728 [Bacillus sp. LM 4-2]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Structures

Toxin

• AlphaFold DB: A0A164X333

Antitoxin